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Table 3 Association between LAP levels and the severity of non-alcoholic fatty liver disease in subjects

From: Lipid accumulation product is a powerful tool to predict non-alcoholic fatty liver disease in Chinese adults

 

Grade

N

Per SD increment of LAPa

P value

P value#

P value##

Men

None

10,266

1 (Ref)

─

─

─

Mild

4621

4.32 (3.94, 4.74)

<0.001

─

─

Moderate

3310

7.07 (6.23, 8.03)

<0.001

<0.001

─

Severe

139

19.61 (11.48, 33.51)

<0.001

<0.001

<0.001

Women

None

18,043

1 (Ref)

─

─

─

Mild

2497

4.90 (4.35, 5.52)

<0.001

─

─

Moderate

1530

7.72 (6.46, 9.23)

<0.001

<0.001

─

Severe

53

23.84 (9.81, 57.90)

<0.001

<0.001

0.015

  1. Adjusted for agea, current smoker, physical activity, education, drinking, alanine transaminasea, total bilirubina, systolic blood pressure, diastolic blood pressure, fasting blood glucosea, platelet count, uric acid, total cholesterol, high-density lipoprotein cholesterol, creatinine, use of antihypertensive and hypoglycemic
  2. a: variables were log-transformed before analysis
  3. #Test of heterogeneity for the effect of LAP levels on the severity of non-alcoholic fatty liver disease: moderate vs mild, severe vs mild
  4. ##Test of heterogeneity for the effect of LAP levels on the severity of non-alcoholic fatty liver disease: severe vs moderate