| Grade |
N
| Per SD increment of LAPa
|
P value |
P value#
|
P value##
|
---|
Men | None | 10,266 | 1 (Ref) | ─ | ─ | ─ |
Mild | 4621 | 4.32 (3.94, 4.74) | <0.001 | ─ | ─ |
Moderate | 3310 | 7.07 (6.23, 8.03) | <0.001 | <0.001 | ─ |
Severe | 139 | 19.61 (11.48, 33.51) | <0.001 | <0.001 | <0.001 |
Women | None | 18,043 | 1 (Ref) | ─ | ─ | ─ |
Mild | 2497 | 4.90 (4.35, 5.52) | <0.001 | ─ | ─ |
Moderate | 1530 | 7.72 (6.46, 9.23) | <0.001 | <0.001 | ─ |
Severe | 53 | 23.84 (9.81, 57.90) | <0.001 | <0.001 | 0.015 |
- Adjusted for agea, current smoker, physical activity, education, drinking, alanine transaminasea, total bilirubina, systolic blood pressure, diastolic blood pressure, fasting blood glucosea, platelet count, uric acid, total cholesterol, high-density lipoprotein cholesterol, creatinine, use of antihypertensive and hypoglycemic
-
a: variables were log-transformed before analysis
-
#Test of heterogeneity for the effect of LAP levels on the severity of non-alcoholic fatty liver disease: moderate vs mild, severe vs mild
-
##Test of heterogeneity for the effect of LAP levels on the severity of non-alcoholic fatty liver disease: severe vs moderate