Variables | T2D + AO (n = 51) | T2D-AO (n = 31) | Control (n = 39) |
---|---|---|---|
Age, years | 56.6 ± 7.5 | 53.4 ± 9.2 | 52.8 ± 9.3 |
Male / female, n | 29 / 22 | 16 / 15 | 21 / 18 |
Duration of diabetes, years (median, IQR) | 4.0 (2.0–8.0) | 3.0 (2.0–5.5) | − |
Diabetes treatment, n | |||
 Diet only | 3 | 2 | − |
 Oral agents | 38 | 24 | − |
 Insulin | 4 | 2 | − |
 Insulin + oral agents | 6 | 3 | − |
Waistline, cm | 91.7 ± 5.9 a, b | 76.6 ± 4.8 | 76.6 ± 4.9 |
BMI, kg/m2 | 25.2 ± 2.7 a, b | 21.1 ± 2.0 | 21.7 ± 2.1 |
Glucose, mmol/L | 7.89 ± 2.06 a | 7.74 ± 2.71 c | 5.07 ± 0.41 |
Insulin, uIU/mL (median, IQR) | 11.35 (9.42–16.07) a, b | 8.57 (6.59–11.77) c | 6.93 (5.06–9.24) |
HOMA-IR (median, IQR) | 4.27 (3.06–5.97) a, b | 2.80 (1.93–4.09) c | 1.51 (1.15–2.08) |
TG, mmol/L | 1.11 ± 0.34 a | 0.79 ± 0.35 | 0.77 ± 0.31 |
TC, mmol/L | 4.80 ± 0.90 a | 4.66 ± 0.81 | 4.32 ± 0.85 |
HDL-C, mmol/L | 1.24 ± 0.28 a | 1.45 ± 0.30 | 1.49 ± 0.36 |
PvuII phenotypes, n | |||
 P+/+ | 31 | 16 | 14 |
 P+/− | 16 | 11 | 19 |
 P−/− | 4 | 4 | 6 |