Skip to main content

Table 2 p53-dependent signaling pathways of milk, acne, and prostate cancer

From: Milk disrupts p53 and DNMT1, the guardians of the genome: implications for acne vulgaris and prostate cancer

Targets Milk Acne PCa References
IGF-1/IGF1R + + + 109,123–130
FOXO1 ? 86–88, 90–94
Androgen/AR + + + 108,145,146
mTORC1 + + + 1114–117
Survivin ? + + 107–109
TRAIL ? 83,84,100–103
IL-6 + + + 141,144–146
miRNA-125b + ? + 15,27,32,33,29,180
miRNA-25 + ? + 27,36,180
  1. IGF-1 insulin-like growth factor 1, IGF1R IGF1 receptor, FOXO1 forkhead box O1, AR androgen receptor, TRAIL tumor necrosis factor-associated apoptosis-inducing ligand, IL-6 interleukin 6