Table 4 Comparison of metabolites concentrations and enzyme activities based on fatty acid ratios between the final and the baseline status (Final vs. Baseline) in group 2 (not meeting the NAFLD criteria at baseline but meeting them during the follow-up)
Metabolites and enzyme activities | Paired Student’s t-test (p-value) | log2 (fold change) |
|---|---|---|
Steroids | 9.05E-03 | −0.38 |
Saturated fatty acids | 1.64E-02 | −0.42 |
Primary fatty amides | 4.26E-02 | −0.34 |
N-Acyl ethanolamines | 2.39E-02 | −0.23 |
1-Monoacylglycerophosphocholine | 2.78E-02 | −0.16 |
Monoacylglycerophosphocholine | 4.00E-02 | −0.14 |
Desaturase (MUFA + PUFA/SFA) | 7.55E-04 | 0.39 |
MAPC/MAPE | 8.21E-04 | −0.34 |
LPC/LPE | 5.71E-04 | −0.31 |
(NEFA) n-6 /n-3 | 3.69E-02 | −0.27 |
De novo lipogenesis (16:0/18:2n-6) | 1.72E-03 | −0.48 |
Stearoyl-CoA desaturase 1 (18:1n-9/18:0) | 1.79E-02 | −0.33 |
Elongase-6 (18:0/16:0) | 3.13E-02 | 0.70 |
Delta-6- desaturase (18:3n-6/18:2n-6) | 2.39E-03 | −0.48 |
Delta-6- desaturase (18:3/18:2) | 7.64E-03 | −0.39 |
Delta-6- desaturase(18:4n-3/18:3n-3) | 1.21E-02 | 2.72 |
Stearoyl-CoA desaturase 1 (16:1n-7/16:0) | 1.11E-02 | 0.11 |
18:1/18:0 | 2.69E-02 | −0.12 |
PUFA/MUFA | 1.50E-02 | 0.25 |