Table 5 Comparison of metabolites concentrations and enzyme activities based on fatty acid ratios between the final and the baseline status (Final vs. Baseline) in group 3 (meeting the NAFLD criteria at baseline but not meeting them during the follow-up)
Metabolites and enzyme activities | Paired Student’s t-test (p-value) | log2 (fold change) |
|---|---|---|
Steroids | 1.99E-02 | −0.46 |
Saturated fatty acids | 1.36E-02 | −0.30 |
1-Monoacylglycerophosphocholine | 2.15E-03 | −0.27 |
2-Monoacylglycerophosphocholine | 2.85E-02 | −0.16 |
Monoacylglycerophosphocholine | 1.16E-02 | −0.20 |
Lysophosphatidylcholines | 1.49E-02 | −0.17 |
1-Monoacylglycerophosphoethanolamine | 1.23E-02 | −0.23 |
MonoetherglycerophosphoethanolaminesO_plasmanyles | 2.12E-02 | −0.32 |
Phospholipase-A2 (LPC/PC) | 8.38E-03 | −0.28 |
Phospholipase-A2 (LPE/PE) | 1.91E-02 | −0.21 |
(NEFA) n-6/n-3 | 1.15E-02 | 0.57 |
De novo lipogenesis (16:0/18:2n-6) | 8.49E-04 | −0.43 |
Stearoyl-CoA desaturase 1 (18:1n-9/18:0) | 2.35E-04 | −0.58 |
Elongase-6 (18:0/16:0) | 6.78E-05 | 0.71 |
Delta-6- desaturase (18:3n-6/18:2n-6) | 4.65E-04 | −0.63 |
Delta-6- desaturase (18:3/18:2) | 2.43E-04 | −0.55 |
Stearoyl-CoA desaturase 1 (16:1n-7/16:0) | 3.22E-03 | 0.11 |
18:1/18:0 | 3.65E-04 | −0.21 |
Lecithin:cholesterolacyltransferase (ChoE/Chol) | 2.64E-02 | 0.47 |