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Table 3 Odds ratios (95% confidence intervals) of incident type 2 diabetes by stratified analysis in the total samples, the Singapore Chinese Health Studya

From: Sex-specific association between fibroblast growth factor 21 and type 2 diabetes: a nested case-control study in Singapore Chinese men and women

Variables

Per 1 log increment of FGF-21

P-interaction

Cases/ controls

OR (95% CI)

Age (year)

  < 60

151/150

1.35 (1.04–1.76)

0.39

  ≥ 60

100/101

1.20 (0.86–1.67)

BMI, kg/m2

  < 23

117/117

1.31 (0.99–1.73)

0.96

  ≥ 23

134/134

1.26 (0.94–1.70)

Physical activity

  < 0.5 h/week

84/148

1.42 (1.12–1.80)

0.46

  ≥ 0.5 h/week

167/103

1.00 (0.65–1.54)

Fasting status

 Fasting

196/194

1.25 (0.99–1.57)

0.64

 Non-fasting

55/57

1.39 (0.87–2.21)

Hs-CRP, mg/L

  < 1.4

74/67

1.38 (1.03–1.85)

0.93

  ≥ 1.4

177/184

1.34 (1.01–1.78)

GGT, IU/L

  < 30

102/140

1.21 (0.91–1.61)

0.18

  ≥ 30

149/111

1.37 (1.00–1.89)

ALT, IU/L

  < 26

96/147

1.26 (0.93–1.69)

0.51

  ≥ 26

155/104

1.30 (0.96–1.77)

TG, mmol/L

  < 1.815

91/140

1.08 (0.82–1.42)

0.18

  ≥ 1.815

160/111

1.42 (1.02–1.97)

HDL-C, mmol/L

  < 0.99

94/157

1.12 (0.80–1.56)

0.87

  ≥ 0.99

157/94

1.26 (0.96–1.65)

  1. aOdds ratios were estimated after adjusting for adjusted for age at blood taken (continuous), smoking (never, ever smoker), alcohol intake (never, ever drinker), weekly moderate-to-vigorous activity (<0.5, ≥0.5 hours/week), education level (primary school and below, secondary or above), history of hypertension (yes, no), fasting status (yes, no) and BMI (continuous), except for stratifying factors
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Nutrition & Metabolism

ISSN: 1743-7075

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