Sex-specific association between fibroblast growth factor 21 and type 2 diabetes: a nested case-control study in Singapore Chinese men and women

Table 5 Summary statistics to assess binary FGF-21 in predicting incident type 2 diabetes risk among female participants, the Singapore Chinese Health Study^a

^aBinary FGF-21 was created using a cutoff point of 123, with a sensitivity of 75.7%, and specificity of 41.4%
^bMultivariable model adjusted for all the variables included in the base model plus binary FGF-21 (<123 vs. ≥ 123 pg/mL)
^cBase model 1 included age (continuous) and BMI (continuous)
^dBase model 2 included variables in base model 1 plus smoking status (never, ever smoker), history of hypertension (yes, no), and levels of TG (mmol/L), HDL-C (mmol/L), and random glucose (mmol/L) (all in quartiles)
^eBase model 3 included variables in base model 2 plus adiponectin (μg/mL) and hs-CRP (mg/L) (both in quartiles)
^fCompared to the base model, the P-values for the differences of AUC after including FGF-21 to the base model were 0.11 for base model 1, 0.56 for base model 2 and 0.41 for model 3

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