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Table 2 Effect of piperonal on Body weight parameters, BMC and BMD in normal and experimental obese rats

From: Antiobesity potential of Piperonal: promising modulation of body composition, lipid profiles and obesogenic marker expression in HFD-induced obese rats

Groups Body weight (g) Lean body mass (g) Total fat (g) Fat free mass (g) Fat % TB H2O (mg) TB Na (mg) TB P (mg) BMC (g) BMD (g/sq./cm)
ND control 301.5±11.0 285.3±8.8 16.3±2.7 130.4±3.5 5.3±0.7 616.5±16.7 1023.7±28.0 2094.1±55.0 8.2 ± 0.69 0.16 ± 0.001
HFD control 506.0±9.3a* 391.3±9.8 a* 114.5±7.1a* 172.8±3.9 a* 22.6±1.3 a* 750.5±24.1 a* 1247.2±40.1 a* 2536.5±79.4 a* 5.5 ± 0.29 a* 0.11 ± 0.002 a*
HFD + Orlistat 5 mg/kg b.wt 450.1±22.8b* 385.3±23.8 b* 64.88±7.4b* 170.3±9.5 b* 14.3±1.7 b* 782.5±52.3 b* 1300.3±87.2 b* 2650.3±166.8 b* 7.1 ± 0.32 b* 0.12 ± 0.001
HFD + Piperonal 20 mg/kg b.wt 490.3±18.0NS 396.8±9.4 93.5±10.2 175.0±3.7 18.9±1.4 781.1±14.9 1298.1±24.8 2636.6±49.4 6.2 ± 0.02 0.13 ± 0.003
HFD + Piperonal 30 mg/kg b.wt 456.0±15.7 b* 376.9±12.6 79.0±6.6 167.1±5.1 17.2±1.2 752.3±25.7 1250.1±43.1 2542.1±84.5 6.6 ± 0.03 0.17 ± 0.002
HFD + Piperonal 40 mg/kg b.wt 454.6±12.3 b* 391.8±8.5 b* 62.8±8.1b* 173.0±3.3 b* 13.7±1.5 b* 798.1±18.7 b* 1326.3±31.1 b* 2693.0±62.0 b* 7.7 ± 0.01 b* 0.14 ± 0.001 b*
  1. Values are mean ± SD, n = 6
  2. Values are statistically significant at *p < 0.05
  3. aSignificantly different from control
  4. bSignificantly different from HFD control