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Table 3 Effect of Piperonal on plasma glucose, insulin and insulin resistance in normal and experimental obese rats

From: Antiobesity potential of Piperonal: promising modulation of body composition, lipid profiles and obesogenic marker expression in HFD-induced obese rats

Groups

Glucose (mg dlāˆ’1)

Insulin (Ī¼U mlāˆ’1)

Insulin resistance

ND control

90.9Ā±7.1

6.0Ā±0.2

3.6Ā±.0.4

HFD Control

150.1Ā±9.7a*

27.2Ā±0.4 a*

6.3Ā±0.2a*

HFDā€‰+ā€‰Orlistat 5Ā mg/kg b.wt

103.1Ā±4.9 b*

15.8Ā±1.4 b*

4.5Ā±0.6 b*

HFDā€‰+ā€‰Piperonal 20Ā mg/kg b.wt

140.7Ā±7.2

24.3.7Ā±0.44

6.0Ā±0.2

HFDā€‰+ā€‰Piperonal 30Ā mg/kg b.wt

131.7Ā±2.3 b*

19.7.4Ā±0.5 b*

5.1Ā±0.2 b*

HFDā€‰+ā€‰Piperonal 40Ā mg/kg b.wt

101.5Ā±5.5 b*

17.9Ā±0.24 b*

4.8Ā±0.3 b*

  1. Values are meanā€‰Ā±ā€‰SD, nā€‰=ā€‰6
  2. Values are statistically significant at *pā€‰<ā€‰0.05
  3. aSignificantly different from normal control
  4. bSignificantly different from HFD control