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Table 1 IC50 values (in μM) for substances tested in LPS-activated RAW264.7 cells

From: Z-ligustilide and anti-inflammatory prostaglandins have common biological properties in macrophages and leukocytes

 

PGE2

 

Nitric Oxide

 
 

Mean ± S.E.M.

N

Mean ± S.E.M.

N

Z-ligustilide

9.3 ± 1.6

33

12.8 ± 1.4

58

15d–PGJ2

2.2 ± 0.5

16

2.3 ± 0.6

25

Rosiglitazone

>50

2

26.9 ± 1.9

16

L-NAME

>500

2

150 ± 12

2

  1. Cells (in triplicates) were incubated with graded amounts of substances, stimulated with 1 μg/mL LPS and cultured for 24 h. PGE2 and NO were measured by EIA and the Griess reaction, respectively, and the IC50 values were calculated for each experimental series. N: number of independent experimental series. L-NAME: L-NG-Nitroarginine methyl ester
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Nutrition & Metabolism

ISSN: 1743-7075

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