Skip to main content

Table 4 Meta-analysis of the FOS supplementation effect on fasting blood glucose and insulin concentrations in rodents

From: Fructo-oligosaccharides and glucose homeostasis: a systematic review and meta-analysis in animal models

Parameter

Metabolic health or diet

Treatment

N

Mean ± SEM

Minimum value

Maximum value

P-value Treatment

Fasting blood glucose, mmol/l

Healthy + unhealthy

Control

15

10.6 ± 1.6

4.8

25.2

0.0124

FOS

17

8.7 ± 1.3

4.6

26.3

Healthy

Control

7

6.8 ± 0.4

4.8

8.3

0.002

FOS

9

6.1 ± 0.4

4.6

8.1

Unhealthy (obese or diabetic)

Control

8

13.9 ± 2.6

5.5

25.2

0.0398

FOS

8

11.5 ± 2.5

4.7

26.3

Low-fat (< 20%E)

Control

7

8.9 ± 2.7

4.8

25.2

0.0083

FOS

9

8.0 ± 2.3

4.6

26.3

High-fat (> 20%E)

Control

8

12.0 ± 1.9

5.7

18.3

0.0225

FOS

8

9.4 ± 1.3

4.7

13.4

Fasting blood insulin, pmol/l

Healthy + unhealthy

Control

6

155.3 ± 29.4

73.7

253

0.0936

FOS

8

116.1 ± 23.8

52.6

225

Healthy

Control

5

135.8 ± 26.9

73.7

214.8

0.5922

FOS

7

122.6 ± 26.5

52.6

225

Unhealthy (obese or diabetic)

Control

1

253.0

–

–

–

FOS

1

70.6

–

–

 

Low-fat (< 20%E)

Control

3

160.1 ± 50.9

77.4

253

0.0136

FOS

5

74.4 ± 10.1

52.6

110

High-fat (>  20%E)a

Control

3

150.5 ± 41.2

73.7

214.8

0.2159

FOS

3

185.7 ± 32.8

120.5

225

  1. E energy, FOS fructo-oligosaccharides
  2. aOnly on healthy animals (not enough data on unhealthy animals)