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Table 3 Myocardial glucose and lipid metabolism

From: Dietary canolol protects the heart against the deleterious effects induced by the association of rapeseed oil, vitamin E and coenzyme Q10 in the context of a high-fat diet

 

C

PS

R

RTC

RTCC

pAkt/totAkt

1.64 ± 0.32

1.52 ± 0.25

1.20 ± 0.29

1.29 ± 0.25

1.52 ± 0.23

PDK4

0.13 ± 0.02a

0.28 ± 0.07ab

0.41 ± 0.08b

0.63 ± 0.09c

0.34 ± 0.03b

TG

20 ± 1a

25 ± 2ab

25 ± 2ab

31 ± 4b

24 ± 2a

DG

1.4 ± 0.2ac

0.9 ± 0.09b

1.3 ± 0.1cd

1.1 ± 0.1bd

0.9 ± 0.1b

NEFA

1.2 ± 0.2a

1.1 ± 0.1ab

1.1 ± 0.1ab

0.9 ± 0.1b

0.9 ± 0.1b

Chol

3.2 ± 0.3a

2.7 ± 0.3ab

2.5 ± 0.1b

2.4 ± 0.1b

2.4 ± 0.1b

CE

2.6 ± 0.6

2.3 ± 0.6

1.1 ± 0.2

1.8 ± 0.4

2.0 ± 0.6

PL

70 ± 3

68 ± 2

65 ± 4

63 ± 4

70 ± 3

  1. C control rats, PS rats fed a palm oil/sunflower oil mixture, R rats fed rapeseed oil, RTC rats fed rapeseed oil enriched with α-tocopherol and coenzyme Q10, RTCC rats fed RTC plus canolol, pAkt/totAKt phosphorylated protein kinase B-to-total protein kinase B ratio, PDK4 pyruvate dehydrogenase kinase-4 mRNA expression, TG, DG, NEFA, Chol, CE, PL amounts of triglycerides, diacylglycerols, non-esterified fatty acids, cholesterol, cholesterol esters and phospholipids, respectively, in the myocardium. Averages of 12 rats per group. Lipid amounts are expressed in mg/g of heart weight
  2. a, b, c, dmeans in a row without a common letter are significantly different