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Table 7 Mean normalised expression of lipogenic and adipokine genes in subcutaneous and retroperitoneal adipose tissue in male and female offspring at 6 weeks of age

From: Exposure to maternal cafeteria diets during the suckling period has greater effects on fat deposition and Sterol Regulatory Element Binding Protein-1c (SREBP-1c) gene expression in rodent offspring compared to exposure before birth

  Male Female
  C-C n = 8 CAF-C n = 4 C-CAF n = 4 CAF-CAF n = 6 C-C n = 9 CAF-C n = 6 C-CAF n = 5 CAF-CAF n = 6
Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM
Subcutaneous
 PPAR-γ 0.05 0.01 0.05 0.01 0.04 0.01 0.05 0.01 0.03 0.00 0.04 0.01 0.02 0.01 0.03 0.01
 FAS 0.58 0.10 0.49 0.10 0.83 0.26 0.73 0.13 0.60 0.04 0.30 0.05 0.24 0.06 0.42 0.15
 G3PDH 0.42 0.06 0.37 0.08 0.37 0.13 0.51 0.09 0.26 0.06 0.21 0.03 0.21 0.08 0.25 0.06
 Adiponectin 1.62 0.27 1.44 0.37 1.75 0.78 2.35 0.30 1.10 0.22 1.13 0.28 0.72 0.19 1.00 0.14
 Leptin 0.12 0.03 0.09 0.03 0.11 0.05 0.20 0.05 0.08 0.02 0.08 0.02 0.05 0.02 0.08 0.01
Retroperitoneal
 PPAR-γ 0.13 0.03 0.19 0.03 0.13 0.03 0.13 0.02 0.16b 0.01 0.10a 0.01 0.14ab 0.01 0.14ab 0.01
 FAS 2.21a 0.48 4.24b 0.60 3.30ab 0.58 2.82ab 0.23 2.85 0.28 2.26 0.50 2.67 0.41 2.63 0.39
 G3PDH 1.31a 0.28 2.80b 0.45 2.13ab 0.35 1.95ab 0.24 1.72 0.18 1.19 0.22 1.70 0.23 1.64 0.21
 Adiponectin 1.62 0.43 1.86 0.39 2.64 0.07 1.72 0.25 1.86b 0.30 0.90a 0.13 1.49b 0.18 1.14a 0.08
 Leptin 0.10 0.03 0.15 0.07 0.22 0.07 0.13 0.01 0.20b 0.04 0.05a 0.01 0.14b 0.04 0.10a 0.01
  1. Values expressed as mean ± SEM, n = 4–6 for all groups. Differences between groups and sexes assessed by 3-way ANOVA. Different superscript letters denote significant differences between groups within each sex and fat depot (P < 0.05)