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Table 1 Comparison of characteristics between subjects with and without CKD (n = 560)

From: The relationship between MnSOD Val16Ala gene polymorphism and the level of serum total antioxidant capacity with the risk of chronic kidney disease in type 2 diabetic patients: a nested case-control study in the Tehran lipid glucose study

  CKD (n = 280) Non-CKD (n = 280) P value
GFR (ml/min/1.73m2) 54.03 (12.81) 67.54 (6.45) <0.001
Age (y) 64 (12.50) 63 (13.75) 0.154
Sex (Male/Female) 105/175 105/175
Duration of diabetes (y) 11.99 (6.4) 11.87 (4.72) 0.417
Body mass index (kg/m2) 28.72 (9.9) 28.47 (3.88) 0.554
Systolic blood pressure (mmHg) 13 (3) 13 (3) 0.203
Diastolic blood pressure (mmHg) 80 (18) 79 (20) 0.581
Use of anti-hypertensive drugs 157 (56.5%) 124 (44.9%) 0.057
Fasting plasma glucose (mg/dl) 143 (23) 136 (38) 0.078
2 h-PG (mg/dl) 227.16 ± 89.431 209.09 ± 91.73 0.896
Use of glucose-lowering drugs 201 (72.3%) 207 (74.7%) 0.510
Total cholesterol (mg/dl) 184 (59) 187.5 (41) 0.702
HDL cholesterol (mg/dl) 47 (12) 46 (20) 0.914
LDL cholesterol (mg/dl) 102.8 (49) 106.8 (43) 0.426
Triglyceride (mg/dl) 154.5 (124) 148 (127) 0.347
Use of lipid-lowering drugs 125 (45%) 112 (40.4%) 0.459
Creatinine (mg/dl) 1.2 (0) 1 (0) <0.001
FRAP (μmol/L) 920 (252.5) 1045 (217.5) <0.001
Current or pervious smoking 19 (6.8%) 14 (5%) 0.375
Hyperlipidemia 48 (17.1%) 47 (16.8%) 0.514
Hypertension 32 (11.4%) 48 (17.1%) 0.138
Obesity (BMI ≥ 30) 103 (36.8%) 104 (37.1%) 0.986
  1. Results are expressed as median (IQR), n (%) or mean ± SD. Mann–Whitney U test, t-test or Chi square test P value. CKD = chronic kidney disease. CKD was defined as estimated glomerular filtration rate < 60 ml/min/1.73 m2. GFR glomerular filtration rate, HDL high density lipoprotein, LDL low density lipoprotein, FRAP Ferric Reducing Ability of Plasma. The values given in italic in P-value column are significant