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Table 1 Comparison of characteristics between subjects with and without CKD (n = 560)

From: The relationship between MnSOD Val16Ala gene polymorphism and the level of serum total antioxidant capacity with the risk of chronic kidney disease in type 2 diabetic patients: a nested case-control study in the Tehran lipid glucose study

 

CKD (n = 280)

Non-CKD (n = 280)

P value

GFR (ml/min/1.73m2)

54.03 (12.81)

67.54 (6.45)

<0.001

Age (y)

64 (12.50)

63 (13.75)

0.154

Sex (Male/Female)

105/175

105/175

–

Duration of diabetes (y)

11.99 (6.4)

11.87 (4.72)

0.417

Body mass index (kg/m2)

28.72 (9.9)

28.47 (3.88)

0.554

Systolic blood pressure (mmHg)

13 (3)

13 (3)

0.203

Diastolic blood pressure (mmHg)

80 (18)

79 (20)

0.581

Use of anti-hypertensive drugs

157 (56.5%)

124 (44.9%)

0.057

Fasting plasma glucose (mg/dl)

143 (23)

136 (38)

0.078

2 h-PG (mg/dl)

227.16 ± 89.431

209.09 ± 91.73

0.896

Use of glucose-lowering drugs

201 (72.3%)

207 (74.7%)

0.510

Total cholesterol (mg/dl)

184 (59)

187.5 (41)

0.702

HDL cholesterol (mg/dl)

47 (12)

46 (20)

0.914

LDL cholesterol (mg/dl)

102.8 (49)

106.8 (43)

0.426

Triglyceride (mg/dl)

154.5 (124)

148 (127)

0.347

Use of lipid-lowering drugs

125 (45%)

112 (40.4%)

0.459

Creatinine (mg/dl)

1.2 (0)

1 (0)

<0.001

FRAP (μmol/L)

920 (252.5)

1045 (217.5)

<0.001

Current or pervious smoking

19 (6.8%)

14 (5%)

0.375

Hyperlipidemia

48 (17.1%)

47 (16.8%)

0.514

Hypertension

32 (11.4%)

48 (17.1%)

0.138

Obesity (BMI ≥ 30)

103 (36.8%)

104 (37.1%)

0.986

  1. Results are expressed as median (IQR), n (%) or mean ± SD. Mann–Whitney U test, t-test or Chi square test P value. CKD = chronic kidney disease. CKD was defined as estimated glomerular filtration rate < 60 ml/min/1.73 m2. GFR glomerular filtration rate, HDL high density lipoprotein, LDL low density lipoprotein, FRAP Ferric Reducing Ability of Plasma. The values given in italic in P-value column are significant