Table 3 Association between the PPP1R3B polymorphisms and the risk of CAD and IS
SNP/Model | Genotype | OR (95%CI)CAD | P CAD | OR (95%CI)IS | P IS |
|---|---|---|---|---|---|
rs12785 | |||||
 Dominant | TT | 1.00 | 1.00 | ||
|  | TA + AA | 1.32(1.02–1.71) | 0.009 | 1.12(0.86–1.46) | 0.405 |
 Log-additive | – | 1.25(1.02–1.54) | 0.007 | 1.16(0.94–1.42) | 0.178 |
rs330910 | |||||
 Dominant | AA | 1.00 | 1.00 | ||
|  | AT+TT | 1.35(1.04–1.76) | 0.006 | 1.03(0.79–1.36) | 0.812 |
 Log-additive | – | 1.29(1.04–1.60) | 0.004 | 1.08(0.87–1.35) | 0.489 |
rs330915 | |||||
 Dominant | AA | 1.00 | 1.00 | ||
|  | AT+TT | 1.15(0.88–1.51) | 0.291 | 1.15(0.87–1.51) | 0.330 |
 Log-additive | – | 1.19(0.95–1.49) | 0.122 | 1.16(0.92–1.47) | 0.218 |
rs9949 | |||||
 Dominant | GG | 1.00 | 1.00 | ||
|  | GA + AA | 1.31(1.02–1.73) | 0.010 | 1.14(0.87–1.48) | 0.341 |
 Log-additive | – | 1.25(1.02–1.53) | 0.008 | 1.17(0.95–1.44) | 0.137 |