|
Factor
|
rs12785
|
rs330910
|
rs330915
|
rs9949
|
|---|
|
P
CAD
|
P
IS
|
P
CAD
|
P
IS
|
P
CAD
|
P
IS
|
P
CAD
|
P
IS
|
|---|
|
Sex (female vs. male)
|
0.015
|
0.80
|
0.006
|
0.30
|
0.79
|
0.45
|
0.017
|
0.80
|
|
Age (≤ 60 vs. > 60 year)
|
0.84
|
0.41
|
0.75
|
0.12
|
0.50
|
0.71
|
0.85
|
0.42
|
|
BMI (≤ 24 vs. > 24 kg/m2)
|
0.89
|
0.12
|
0.78
|
0.65
|
0.78
|
0.48
|
0.92
|
0.12
|
|
Smoking (yes vs. no)
|
0.64
|
0.010
|
0.57
|
0.15
|
0.29
|
0.026
|
0.62
|
0.010
|
|
Drinking (yes vs. no)
|
0.61
|
0.92
|
0.41
|
0.41
|
0.62
|
0.87
|
0.57
|
0.96
|
|
hypertension (yes vs. no)
|
0.009
|
0.22
|
0.007
|
0.77
|
0.014
|
0.51
|
0.009
|
0.23
|
|
hyperlipidemia (yes vs. no)
|
0.25
|
0.12
|
0.32
|
0.092
|
0.28
|
0.37
|
0.24
|
0.14
|
- PCAD/PIS, the P value between patients and control, BMI body mass index. The P values for interactions of genotypes and gender, age, BMI, drinking, smoking, hypertension, hyperlipidemia on the risk of CAD/IS were obtained from unconditional logistic regression, and a P < 0.0017 was considered statistically significant after Bonferroni correction
