Fig. 5

Effect of glucose on gene expression in rats switched from VLC to an HC diet. Liver samples were obtained from obese rats that had consumed restricted amounts of a VLC diet for 8 weeks and then were switched to isocaloric amounts of the HC diet for 3 (VC3) or 7 (VC7) days (Phase 3); 16 h feed-deprived (dark bars) and 3 h post-glucose (light bars). Relative hepatic gene expression is plotted as 2^-dCt. Means ± SEM are shown. *Different from Feed-deprived, P < 0.05, ** P < 0.01, *** P < 0.001. Acaca: acetyl-CoA carboxylase; Fasn: fatty acid synthase; Gck: glucokinase; Insig2: insulin signaling protein-2; Pck1: phosphoenolpyruvate carboxykinase-1; Scd1: stearoyl-CoA desaturase-1; Srebf1: Sterol regulatory element-binding protein-1