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Table 2 Effects of diet on body composition in male rats1

From: Very low-carbohydrate, high-fat, weight reduction diet decreases hepatic gene response to glucose in obese rats

DIET Body Visceral Total Body Liver Muscle Leptin
Weight (g) Fat (g) Fat (g) Fat (%) Lipid (mg/g) TG (mg/g) ng/mL
Phase 1
 LF 558 ± 24b 39 ± 5.1b 67.2 ± 8.3c 11.3 ± 1.2b 49.9 ± 5.8c 5.9 ± 1.7bcd 11.6 ± 2.1b
 HF1 665 ± 32a 69.0 ± 11.1a 130 ± 17.3ab 19.1 ± 1.9a 73 ± 5.2a 8.1 ± 0.4ab 42.6 ± 8.2a
Phase 2
 HF2 748 ± 13a 78.2 ± 7.2a 148 ± 9.6a 19.7 ± 1.0a 72.1 ± 6.9a 9.5 ± 0.7a 38.9 ± 5.9a
 VLC 628 ± 14b 51.1 ± 3.7ab 92.9 ± 7.8bc 14.7 ± 1ab 52.5 ± 6bc 6.9 ± 1.4bc 14.1 ± 2.2b
 LC 613 ± 0.9b 42.2 ± 3.6b 75.6 ± 5.4c 12.3 ± 0.8b 67.8 ± 4.9ab 5.5 ± 0.7cd 8.7 ± 1.1b
 HC 610 ± 11b 37.9 ± 2.5b 72.5 ± 6.1c 11.9 ± 1b 53 ± 6.9bc 4.5 ± 0.7cd 7.9 ± 1.0b
Phase 3
 VC3 632 ± 10b     60.8 ± 4.2bc 3.4 ± 0.1e 8.6 ± 1.8b
 VC7 644 ± 11b     54.1 ± 3.5bc 4.9 ± 1.1cd 7.4 ± 1.4b
  1. 1Values are means ± SEM. Labeled means in a column without a common letter differ, P < 0.05; the letter a represents the highest value .HOMA-IR units are (mmol/L)(μU/mL)/22.5. LF, lower-fat; HF1, high-fat Phase 1; HF2, high-fat Phase 2; VLC, very low-carbohydrate; LC, low-carbohydrate; HC, high-carbohydrate