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Table 1 Baseline characteristics of participants with and without incident T2DM; Tehran Lipid and Glucose Study (TLGS)

From: Impact of 3-year changes in lipid parameters and their ratios on incident type 2 diabetes: Tehran lipid and glucose study

 

Total

(N = 5474)

With incident T2DM

(N = 577)

Without incident T2DM

(N = 4897)

P-value

Continuous variables

 Age (year)

41.3 ± 13.6

46.7 ± 12.7

40.6 ± 13.6

< 0.001

 SBP (mmHg)

116.95 ± 17.1

124.2 ± 18.2

116.1 ± 16.8

< 0.001

 DBP (mmHg)

76.6 ± 10.4

80.8 ± 10.5

76.1 ± 10.2

< 0.001

 Baseline BMI (kg/m2)

26.7 ± 4.5

29.1 ± 4.6

26.4 ± 4.4

< 0.001

 Baseline WC (cm)

87.6 ± 11.8

94.6 ± 11.1

86.8 ± 11.6

< 0.001

 Baseline FPG (mmol/L)

4.95 ± 0.51

5.36 ± 0.60

4.90 ± 0.47

< 0.001

 TC (mmol/L)

5.29 ± 1.16

5.74 ± 1.26

5.24 ± 1.13

< 0.001

 LnTG

0.44 ± 0.54

0.70 ± 0.52

0.40 ± 0.54

 

 HDL-C (mmol/L)

1.09 ± 0.28

1.06 ± 0.27

1.09 ± 0.28

0.005

 LDL-C (mmol/L)

3.37 ± 0.94

3.68 ± 1.00

3.33 ± 0.92

< 0.001

 Non-HDL-C (mmol/L)

4.20 ± 1.16

4.68 ± 1.25

4.15 ± 1.14

< 0.001

 LnTG/HDL-C

0.38 ± 0.69

0.68 ± 0.65

0.35 ± 0.69

 

 TC/HDL-C

5.16 ± 1.68

5.70 ± 1.73

5.09 ± 1.66

< 0.001

 BMI change (Kg/m2)

0.79 ± 1.97

0.98 ± 2.50

0.77 ± 1.90

0.06

 WC change (cm)

3.64 ± 6.79

3.99 ± 6.60

3.59 ± 6.81

0.18

 FPG change (mmol/L)

0.03 ± 0.50

0.16 ± 0.57

0.02 ± 0.49

< 0.001

Categorical variables

 Male

2320(42.4)

237(41.1)

2083(42.5)

0.53

 Hypertension (%)

951 (17.4)

174(30.2)

777(15.9)

< 0.001

 Family history of T2DM (%)

1397(25.5)

212(36.7)

1185(24.2)

< 0.001

 CVD history (%)

171(3.1)

30(5.2)

141(2.9)

0.005

 Education level (%)

   

< 0.001

   ≥ 12 years

752(13.7)

51(8.8)

701(14.3)

 

  6–12 years

3070(56.1)

276(47.8)

2794(57.1)

 

   < 6 years

1652(30.2)

250(43.3)

1402(28.6)

 

 Intervention (%)

2425(44.3)

239(41.4)

2186(44.6)

0.14

 Smoking (%)

   

0.74

  Never or past

4832(88.4)

513(89.1)

4319(88.3)

 

  Current

634(11.6)

63(10.9)

571(11.7)

 

 Lipid drug use (%)

125(2.3)

27(4.7)

98(2.0)

< 0.001

  1. Values are mean ± SD for continuous variables, and n (%) for categorical variables
  2. T2DM type 2 diabetes, SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, WC waist circumferences, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, CVD cardiovascular diseases
  3. LDL-C values were calculated using the modified Friedewald formula