Skip to main content

Table 4 Hazard ratios for predicting type 2 diabetes in different models of tertiles of changes in lipid components, Tehran Lipid and Glucose Study (1999–2015)

From: Impact of 3-year changes in lipid parameters and their ratios on incident type 2 diabetes: Tehran lipid and glucose study

Lipid parameters

1sttertile changing value

2ndtertile changing value

3rdtertile changing value

P trend

AIC

Harrell’s C

 

HR (95%CI)

HR (95%CI)

HR(95%CI)

   

TC (mmol/L)

 Model 1

1.00

1.08(0.88–1.33)

1.13 (0.90–1.40)

0.56

9496

0.65

 Model 2

1.00

1.11(0.91–1.37)

1.25(1.001–1.56)

0.14

9050

0.78

 Model 3

1.00

1.07(0.87–1.32)

1.16 (0.92–1.45)

0.46

9031

0.78

 Model 4

1.00

0.97(0.79–1.19)

0.95(0.76–1.18)

0.89

8842

0.81

LnTG

 Model 1

1.00

1.08(0.86–1.36)

1.49(1.22–1.82)

< 0.001

9401

0.69

 Model 2

1.00

1.03(0.82–1.30)

1.39(1.13–1.70)

0.002

9022

0.78

 Model 3

1.00

0.99(0.78–1.24)

1.29(1.05–1.59)

0.013

9003

0.79

 Model 4

1.00

0.92(0.73–1.16)

1.22(0.99–1.49)

0.026

8819

0.81

HDL-C (mmol/L)

 Model 1

1.00

0.85(0.68–1.05)

0.74(0.58–0.95)

0.06

9502

0.65

 Model 2

1.00

0.90(0.72–1.12)

0.84(0.66–1.07)

0.35

9051

0.77

 Model 3

1.00

0.91(0.73–1.13)

0.86(0.68–1.10)

0.49

9031

0.78

 Model 4

1.00

0.87(0.70–1.08)

0.81(0.64–1.04)

0.25

8842

0.81

LDL-C (mmol/L)

 Model 1

1.00

1.13(0.92–1.40)

1.20(0.97–1.49)

0.25

9504

0.65

 Model 2

1.00

1.16(0.94–1.43)

1.28(1.03–1.59)

0.08

9050

0.78

 Model 3

1.00

1.12(0.91–1.38)

1.21(0.97–1.50)

0.24

9031

0.78

 Model 4

1.00

1.03(0.83–1.27)

1.00(0.80–1.25)

0.96

8844

0.81

Non-HDL-C (mmol/L)

 Model 1

1.00

1.02(0.82–1.26)

1.31(1.06–1.62)

0.019

9479

0.66

 Model 2

1.00

1.05(0.85–1.29)

1.45(1.17–1.80)

0.001

9039

0.78

 Model 3

1.00

1.01(0.82–1.25)

1.35(1.08–1.68)

0.008

9022

0.78

 Model 4

1.00

0.94(0.76–1.16)

1.11(0.89–1.38)

0.32

8839

0.81

LnTG/HDL-C

 Model 1

1.00

1.23(0.97–1.55)

1.53(1.25–1.86)

< 0.001

9414

0.68

 Model 2

1.00

1.12(0.89–1.42)

1.42(1.16–1.74)

0.002

9025

0.78

 Model 3

1.00

1.09(0.86–1.38)

1.33(1.08–1.63)

0.016

9007

0.79

 Model 4

1.00

1.12(0.88–1.42)

1.33(1.08–1.63)

0.019

8823

0.81

TC/HDL-C

 Model 1

1.00

1.22(0.98–1.52)

1.47(1.19–1.82)

0.002

9474

0.66

 Model 2

1.00

1.12(0.90–1.39)

1.43(1.16–1.77)

0.002

9039

0.78

 Model 3

1.00

1.09(0.87–1.36)

1.35(1.09–1.67)

0.013

9022

0.78

 Model 4

1.00

1.09(0.87–1.36)

1.27(1.02–1.57)

0.08

8838

0.81

  1. TC: total cholesterol, TG: triglyceride, HDL-C: high density lipoprotein cholesterol, LDL-C: low density lipoprotein cholesterol, HR: hazard ratio, CI: confidence interval, AIC:Akaike's information criteria. 
  2. Model 1: adjusted for age, sex, and baseline measurements of lipid profile
  3. Model 2: adjusted for age sex, education, lipid drug use, family history of type 2 diabetes, history of cardiovascular disease, hypertension and baseline measurements of fasting plasma glucose (FPG), body mass index (BMI), waist circumferences (WC) and lipid profile
  4. Model 3: model 2+ BMI change
  5. Model 4: model 3+ FPG change
Back to article page

Nutrition & Metabolism

ISSN: 1743-7075

Contact us