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Table 4 Generalized linear models of the effects of the IL6 -174G/C polymorphism on the body composition of severely obese individuals after a 12-week nutritional intervention

From: PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial

Variables Weight change Fat mass change
Adj. β* 95% CI P Adj. β* 95% CI P
Intercept 3.969 − 4.212, 11.348 0.369 −0.754 −9.145, 7.363 0.860
Age 0.026 −0.068, 0.121 0.585 −0.027 −0.112, 0.586 0.541
Gender
 Females 0 Reference   Reference  
 Males −2.411 −4.752, −0.070 0.044 1.281 −1.725, 4.286 0.404
Baseline BMI −0.053 −0.188, 0.081 0.437 0.071 −0.110, 0.253 0.442
Sedentary time change 0.008 −0.005, 0.021 0.235 0.003 −0.008, 0.142 0.588
Nutritional intervention
 OO 0 Reference   Reference  
 DieTBra −4.980 −7.103, −2.858 < 0.001 −1.495 −3.390, 0.400 0.122
 DieTBra+OO −4.406 −6.478, −2.335 < 0.001 −1.975 −3.798, −0.153 0.034
-174G > C polymorphism
 GG 0 Reference   Reference  
 C carriers −0.219 −1.956, 1.519 0.805 −0.015 −1.513, 1.484 0.985
  1. Dependent variables: 12th week measurement – baseline measurement. OO olive oil group, DieTBra traditional Brazilian diet group, DieTBra + OO traditional Brazilian diet plus olive oil group, BMI Body Mass Index
  2. *General linear models were adjusted for age, gender, baseline BMI and change in sedentary time. When interactions were tested (SNP x nutritional intervention, gender x nutritional intervention), the P value was not significant (P > 0.05). Data for the outcomes fat-free mass, body fat percentage and lean mass were not significant