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Table 4 Generalized linear models of the effects of the IL6 -174G/C polymorphism on the body composition of severely obese individuals after a 12-week nutritional intervention

From: PPARG2 Pro12Ala polymorphism influences body composition changes in severely obese patients consuming extra virgin olive oil: a randomized clinical trial

Variables

Weight change

Fat mass change

Adj. β*

95% CI

P

Adj. β*

95% CI

P

Intercept

3.969

− 4.212, 11.348

0.369

−0.754

−9.145, 7.363

0.860

Age

0.026

−0.068, 0.121

0.585

−0.027

−0.112, 0.586

0.541

Gender

 Females

0

Reference

 

Reference

 

 Males

−2.411

−4.752, −0.070

0.044

1.281

−1.725, 4.286

0.404

Baseline BMI

−0.053

−0.188, 0.081

0.437

0.071

−0.110, 0.253

0.442

Sedentary time change

0.008

−0.005, 0.021

0.235

0.003

−0.008, 0.142

0.588

Nutritional intervention

 OO

0

Reference

 

Reference

 

 DieTBra

−4.980

−7.103, −2.858

< 0.001

−1.495

−3.390, 0.400

0.122

 DieTBra+OO

−4.406

−6.478, −2.335

< 0.001

−1.975

−3.798, −0.153

0.034

-174G > C polymorphism

 GG

0

Reference

 

Reference

 

 C carriers

−0.219

−1.956, 1.519

0.805

−0.015

−1.513, 1.484

0.985

  1. Dependent variables: 12th week measurement – baseline measurement. OO olive oil group, DieTBra traditional Brazilian diet group, DieTBra + OO traditional Brazilian diet plus olive oil group, BMI Body Mass Index
  2. *General linear models were adjusted for age, gender, baseline BMI and change in sedentary time. When interactions were tested (SNP x nutritional intervention, gender x nutritional intervention), the P value was not significant (P > 0.05). Data for the outcomes fat-free mass, body fat percentage and lean mass were not significant