Switching from a high-fat cellulose diet to a high-fat pectin diet reverses certain obesity-related morbidities

Nutrition & Metabolism

Table 2 Body weight of mice switched from HFC to LFC, LFP, HFP and HFC

Starting Diet	Baseline Body Weight (g)	Switch Diet	Weeks Post-Switch Body Weight (g)
Starting Diet	Baseline Body Weight (g)	Switch Diet	1	2	3	4	5
LFC	23.99 ± 0.30	–	26.54 ± 0.39	26.94 ± 0.40	26.98 ± 0.45	27.29 ± 0.53	27.02 ± 0.52
HFC	37.29 ± 0.62^#	LFP	27.54 ± 0.89^c	26.92 ± 0.59^c	28.00 ± 0.31^c	28.88 ± 0.44^c	27.81 ± 0.42^c
		LFC	29.53 ± 1.18^c	28.78 ± 0.97^c	29.11 ± 0.76^#,c	29.48 ± 1.05^c	29.00 ± 1.07^c
		HFP	35.22 ± 1.34^#,a	35.41 ± 1.17^#,a	35.94 ± 1.16^#,a	36.96 ± 1.37^#,a	37.93 ± 1.48^#,a
		HFC	39.89 ± 1.47^#,b	42.20 ± 1.73^#,b	44.35 ± 1.78^#,b	46.28 ± 1.96^#,b	46.98 ± 1.98^#,b

Mice were fed HFC as the starting diet for 12 weeks then switched to LFP, LFC, HFP, or HFC. Mice fed LFC as the starting diet were maintained on LFC as control. Results are expressed as mean ± s.e.m.; n = 10–11. Points without a common superscript are different (p < 0.05). # indicates significance versus LFC control (p < 0.05)

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