Switching from a high-fat cellulose diet to a high-fat pectin diet reverses certain obesity-related morbidities

Nutrition & Metabolism

Table 4 Impact on locomotion of switching from HFC to LFC, LFP, HFP and HFC

Starting Diet	Baseline	Switch Diet	Weeks Post-Switch Locomotor Activity (cm)
Starting Diet	Baseline	Switch Diet	3	5
LFC	1502.66 ± 80.20^a	–	1533.83 ± 111.39	1834.80 ± 133.71
HFC	1232.45 ± 56.27^b	LFP	1470.25 ± 68.30^a	1818.48 ± 103.93^a
		LFC	1404.95 ± 90.70^a	1904.84 ± 102.28^a
		HFP	924.76 ± 86.23^b,#	1136.88 ± 132.45^b,#
		HFC	1001.79 ± 81.53^b,#	1340.66 ± 79.74^b,#

Mice were fed HFC as the starting diet for 12 weeks then switched to LFP, LFC, HFP, or HFC. Mice fed LFC as the starting diet were maintained on LFC as control. Results are expressed as mean ± s.e.m.; n = 10–11. Points without a common superscript are different within each week post-switch (p < 0.05). # indicates significance versus LFC control within each week post switch (p < 0.05)

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