Fig. 3

GABA regulates the mRNA expression of the major pro- and anti-apoptotic factors in RINm5F. Real-time quantitative measurement of Caspase-3 a Bax b and Bcl-2 c mRNA levels in RINm5F cells. Data are shown as the mean ± SD of three independent experiments (n = 4). Means with different lower-case letters are significantly different (P < 0.05). Control, control medium; H₂O₂, medium containing 100 μM H₂O₂; H₂O₂ + (50 μM, 100 μM, 200 μM) GABA, medium containing 100 μM H₂O₂ and GABA