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Table 4 Lipoprotein particle number and cholesterol content at wk. 12 and changes from baseline in womena

From: Consumption of regular-fat vs reduced-fat cheese reveals gender-specific changes in LDL particle size - a randomized controlled trial

  RED (n = 21) RED (n = 21) CHO (n = 20) REG vs. RED REG vs. CHO
Week 12 Change from baseline Week 12 Change from baseline Week 12 Change from baseline P P
VLDL-P (nmol/l) 135.6 ± 13.5 − 11.2 ± 20.0 126.7 ± 10.6 − 10.4 ± 10.3 104.4 ± 13.3 − 6.4 ± 7.0 0.59 0.25
IDL-P (nmol/L) 68.8 ± 6.1 −4.9 ± 9.3 68.5 ± 6.8 − 7.6 ± 5.7 63.7 ± 7.2 1.3 ± 5.5 0.75 0.91
LDL-P (nmol/l)
Total 1343.0 ± 57.4 72.4 ± 53.1 1238.3 ± 81.0 − 30.9 ± 49.4 1359.7 ± 71.9 11.3 ± 52.7 0.08 0.83
LDL1 + 2 449.9 ± 24.1 31.0 ± 19.6 459.9 ± 25.0 −14.2 ± 23.0 497.4 ± 23.5 − 22.3 ± 21.0 0.41 0.68
LDL3 + 4 471.6 ± 19.2 45.2 ± 25.5 408.4 ± 35.1 − 0.5 ± 17.7 422.8 ± 26.2 1.2 ± 24.1 0.24 0.51
LDL5 + 6 451.8 ± 42.6 −9.1 ± 25.9 354.5 ± 37.7 31.4 ± 23.6 407.7 ± 47.3 25.2 ± 18.8 0.17 0.25
VLDL-C (mg/dl)
Total 13.8 ± 2.0 −1.9 ± 3.0 12.7 ± 1.8 −2.0 ± 1.6 9.1 ± 2.1 − 0.9 ± 1.2 0.65 0.30
VLDL1 + 2 5.8 ± 1.2 0.1 ± 1.2 4.5 ± 1.0 − 0.8 ± 0.8 2.9 ± 1.1 −0.4 ± 0.6 0.31 0.21
VLDL3 + 4 5.6 ± 0.8 − 1.8 ± 1.7 5.6 ± 0.9 − 1.3 ± 0.9 4.1 ± 0.9 − 0.7 ± 0.5 0.94 0.51
VLDL5 + 6 2.0 ± 0.1 − 0.1 ± 0.2 2.1 ± 0.1 0.0 ± 0.1 1.8 ± 0.1 0.0 ± 0.1 0.62 0.83
IDL-C (mg/dl) 5.9 ± 0.9 −0.6 ± 1.1 7.3 ± 1.3 − 1.6 ± 1.6 6.1 ± 1.2 − 0.2 ± 0.8 0.83 0.60
LDL-C (mg/dl)
Total 121.3 ± 5.7 8.3 ± 5.5 114.9 ± 7.9 0.4 ± 4.8 124.6 ± 6.0 −0.3 ± 5.2 0.21 0.79
LDL1 + 2 46.4 ± 2.9 3.4 ± 2.2 48.2 ± 2.8 −0.6 ± 2.7 51.9 ± 2.5 −2.3 ± 2.2 0.60 0.74
LDL3 + 4 40.0 ± 2.2 3.9 ± 2.3 39.4 ± 3.4 0.8 ± 1.9 40.9 ± 2.6 − 0.4 ± 2.4 0.37 0.53
LDL5 + 6 33.7 ± 3.2 −0.2 ± 1.7 26.6 ± 3.0 −1.7 ± 1.7 30.7 ± 3.5 2.0 ± 1.5 0.19 0.29
HDL-C (mg/dl)
Total 61.2 ± 3.2 2.8 ± 1.2 57.9 ± 2.8 2.7 ± 1.4 59.2 ± 2.8 −1.3 ± 1.8 0.73 0.02
HDL1 + 2 31.7 ± 3.1 1.1 ± 1.0 28.9 ± 2.4 0.9 ± 1.1 32.1 ± 2.4 −0.3 ± 1.5 0.77 0.21
HDL3 + 4 30.1 ± 1.0 1.6 ± 0.8 29.3 ± 1.0 1.6 ± 0.7 27.7 ± 1.0 −1.2 ± 0.7 0.63 0.006
LDL-C:HDL-C ratio 2.1 ± 0.1 0.1 ± 0.1 2.1 ± 0.2 −0.1 ± 0.1 2.2 ± 0.1 0.1 ± 0.1 0.20 0.69
Apo-B:Apo-A1 ratio 0.6 ± 0.0 0.0 ± 0.0 0.6 ± 0.0 0.0 ± 0.0 0.6 ± 0.0 0.0 ± 0.0 0.23 0.19
  1. aAll values are means ± SEMs. Statistical differences between groups are based on linear mixed models with baseline values as covariates and adjustments for age, BMI and change in body fat. Pairwise comparisons were made using post hoc t-test on the linear mixed model with p-values adjusted for multiplicity. Abbreviations: Apo apolipoprotein, CHO carbohydrate control, HDL-C high density lipoprotein cholesterol, IDL-C intermediate density lipoprotein cholesterol, IDL-P intermediate density lipoprotein particle number, LDL-C low density lipoprotein cholesterol, LDL-P low density lipoprotein particle number, RED reduced-fat cheese, REG regular-fat cheese, VLDL-C very low density lipoprotein cholesterol, VLDL-P very low density lipoprotein particle number