Fig. 2

ALA increased body proportion of muscle mass, and mean cross section area in OLETF rats. The end of the 8 week study, gastronecmius weighted for morphometric assessment and expressed as tissue mass g per g body weight. a Relative muscle mass b representative macrographs of hematoxylin and eosin (H&E) stained gastrocnemius muscle sections in LETO and OLETF rats (X100). Scale bar = 100 μm. Fiber (c) mean cross-sectional area (CSA) and d distribution in LETO and OLETF gastrocnemius muscle. Data presented as mean ± SEM (n = 5–6 rats per group). *: P < 0.05 vs. LETO-C. #: P < 0.05 vs. OLETF-C