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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Alpha-lipoic acid preserves skeletal muscle mass in type 2 diabetic OLETF rats

Fig. 5

ALA upregulated protein expression levels of AMPK, SIRT1, and PGC-1α in the skeletal muscles of OLETF rats. The phosphorylation of AMPK and p38 MAPK, and AMPK, SIRT1, PGC-1α, p38 MAPK expression levels in rat skeletal muscle were determined after 8 weeks of ALA treatment using a western blot analyses, b scanning densitometry. Band intensities of SIRT1 and PGC-1α were normalized to GAPDH. Data presented as mean ± SEM (n = 6 rats per group)

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