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Table 2 Circulating lipids and glucose metabolism markers

From: Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

  SD n = 7 FFC n = 14 FFC/SD n = 14 Overall P value
Triglyceride (mM)
 Mid-study 0.38 (0.29–0.41) 0.57 (0.37–0.76)* 0.48 (0.33–0.52) 0.04
 Termination 0.34 (0.29–0.35)b 0.63 (0.54–0.88)h** 0.36 (0.32–0.45)g††† <.0001
Total cholesterol (mM)
 Mid-study 2.0 (1.6–2.2) 14.1 (11.1–22.1)*** 14.6 (11.2–18.7)*** 0.0003
 Termination 1.7 (1.6–2.2)b 11.9 (11.0–13.2)h*** 1.9 (1.6–2.0)g†††† <.0001
Glucose (mM)
 Mid-study 3.8 (3.5–4.0) 4.0 (3.9–4.2)h 3.9 (3.6–4.2)f 0.3
 Termination 3.4 (3.2–3.6)b 3.7 (3.6–3.9) 3.8 (3.7–4.0)e 0.05
KG (min−1)
 Mid-study 3.1 (2.8–4.9) 2.2 (1.9–2.4)h** 2.1 (1.9–2.1)** 0.005
 Termination 3.2 (2.7–3.5)b 2.1 (1.8–2.4)h** 3.2 (2.5–3.6) 0.01
AUCInsulin (pM*min)
 Mid-study 6983 (6344–12,602) 10,519 (9780–16,901)h 11,834 (10996–14,716)d 0.2
 Termination 12,573 (11507–20,683)a 27,168 (17204–35,562)h 24,032 (20478–28,147)c 0.07
  1. Data is presented as median and interquartile range (25th–75th)
  2. SD fed standard chow, FFC fed fat/fructose/cholesterol-rich diet, FFC/SD dietary normalization, KG intravenous glucose tolerance index, AUCInsulin area under the curve of insulin
  3. *P < 0.05; **P < 0.01; ***P < 0.001, significantly different from SD, P < 0.05; †††P < 0.001; ††††P < 0.0001, significantly different from FFC
  4. a n = 5
  5. b n = 6
  6. c n = 8
  7. d n = 9
  8. e n = 10
  9. f n = 11
  10. g n = 12
  11. h n = 13