Fig. 1

Weight, glucose and insulin tolerance measured during the study. a – Body weight evolution for the whole experiment. c control (n = 24 for 3 to 9 weeks, and n = 8 for 9 to 15 weeks). Ex: Exercise standard diet (n = 8). FF: fructose supplemented (n = 26 for 3 to 9 weeks and n = 8 for 9 to 15 weeks). ExFF: Exercise fructose supplemented (n = 10). b - Effect of training and fructose supplementation on blood glucose levels during OGTT, 15, 30, 45, 60, 90, 120 min after glucose charge in all groups, after subtracting baseline concentrations at 13 weeks old. c - Evolution of net glucose AUC in the four rat groups at 13 weeks old. d - Effect of training and fructose supplementation on plasma insulin levels during OGTT after subtracting baseline concentrations at 13 weeks old.*C compared to FF (***p < 0.001). e - Evolution of net insulin AUC in the four rat groups at 13 weeks old. For a, b, c, d, e figures: groups C: control (n = 7). Ex: Exercise standard diet (n = 8). FF: fructose supplemented (n = 7). ExFF: Exercise fructose supplemented (n = 10). Values are means ± SEM. For C and E figures, statistical differences with post-hoc test are observed when lowercase letters (a, b) are different with p < 0.05