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Table 1 General characteristics and serum lipid levels between the controls and patients

From: ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin cholesterol-lowering responses

Characteristic Control CAD IS P 1 P 2 P 3
Number 549 568 537    
Male/female 384/165 419/149 389/148 0.155 0.364 0.619
Age, years 61.87±11.12 62.23±10.59 62.80±12.41 0.589 0.196 0.408
Body mass index, kg/m2 22.28±2.82 23.85±3.37 23.43±3.52 <0.001 <0.001 0.041
Systolic blood pressure, mmHg 130.00±20.60 132.97±23.16 147.58±21.96 0.024 <0.001 <0.001
Diastolic blood pressure, mmHg 82.38±13.01 79.05±14.06 83.71±12.95 <0.001 0.092 <0.001
Pulse pressure, mmHg 49.53±14.92 53.83±17.59 63.83±17.96 <0.001 <0.001 <0.001
Cigarette smoking, n (%) 235 (42.8) 246 (43.3) 224 (41.7) 0.865 0.716 0.592
Alcohol consumption, n (%) 245 (44.6) 132 (23.2) 144 (26.8) <0.001 <0.001 0.170
Total cholesterol, mmol/L 4.92±1.11 4.51±1.23 4.52±1.14 <0.001 <0.001 0.836
Triglyceride, mmol/L 1.01 (0.64) 1.36 (0.94) 1.35 (0.93) <0.001 <0.001 0.467
HDL-C, mmol/L 1.90±0.49 1.14±0.34 1.23±0.40 <0.001 <0.001 <0.001
LDL-C, mmol/L 2.74±0.79 2.71±1.01 2.68±0.90 0.549 0.245 0.638
Apolipoprotein (Apo) A1, g/L 1.40±0.24 1.04±0.52 1.02±0.22 <0.001 <0.001 0.608
ApoB, g/L 0.90±0.21 1.11±0.75 0.89±0.25 0.313 0.502 0.302
ApoA1/ApoB 1.63±0.47 1.34±0.46 1.17±0.61 0.009 <0.001 0.117
Type 2 diabetes, n (%) 43 (7.8) 91 (16.0) 81 (15.1) <0.001 <0.001 0.668
Hypertension, n (%) 157 (28.6) 200 (35.2) 285 (53.1) 0.018 <0.001 <0.001
Hyperlipidemia, n (%) 175 (31.9) 220 (38.7) 238 (44.3) 0.017 <0.001 0.100
  1. CAD coronary artery disease, IS ischemic stroke, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol. The value of triglyceride was presented as median (interquartile range), the difference between CAD/IS patients and controls was determined by the Wilcoxon-Mann-Whitney test. P1, CAD vs. controls; P2, IS vs. controls; P3, CAD vs. IS