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Table 1 General characteristics and serum lipid levels between the controls and patients

From: ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin cholesterol-lowering responses

Characteristic

Control

CAD

IS

P 1

P 2

P 3

Number

549

568

537

   

Male/female

384/165

419/149

389/148

0.155

0.364

0.619

Age, years

61.87±11.12

62.23±10.59

62.80±12.41

0.589

0.196

0.408

Body mass index, kg/m2

22.28±2.82

23.85±3.37

23.43±3.52

<0.001

<0.001

0.041

Systolic blood pressure, mmHg

130.00±20.60

132.97±23.16

147.58±21.96

0.024

<0.001

<0.001

Diastolic blood pressure, mmHg

82.38±13.01

79.05±14.06

83.71±12.95

<0.001

0.092

<0.001

Pulse pressure, mmHg

49.53±14.92

53.83±17.59

63.83±17.96

<0.001

<0.001

<0.001

Cigarette smoking, n (%)

235 (42.8)

246 (43.3)

224 (41.7)

0.865

0.716

0.592

Alcohol consumption, n (%)

245 (44.6)

132 (23.2)

144 (26.8)

<0.001

<0.001

0.170

Total cholesterol, mmol/L

4.92±1.11

4.51±1.23

4.52±1.14

<0.001

<0.001

0.836

Triglyceride, mmol/L

1.01 (0.64)

1.36 (0.94)

1.35 (0.93)

<0.001

<0.001

0.467

HDL-C, mmol/L

1.90±0.49

1.14±0.34

1.23±0.40

<0.001

<0.001

<0.001

LDL-C, mmol/L

2.74±0.79

2.71±1.01

2.68±0.90

0.549

0.245

0.638

Apolipoprotein (Apo) A1, g/L

1.40±0.24

1.04±0.52

1.02±0.22

<0.001

<0.001

0.608

ApoB, g/L

0.90±0.21

1.11±0.75

0.89±0.25

0.313

0.502

0.302

ApoA1/ApoB

1.63±0.47

1.34±0.46

1.17±0.61

0.009

<0.001

0.117

Type 2 diabetes, n (%)

43 (7.8)

91 (16.0)

81 (15.1)

<0.001

<0.001

0.668

Hypertension, n (%)

157 (28.6)

200 (35.2)

285 (53.1)

0.018

<0.001

<0.001

Hyperlipidemia, n (%)

175 (31.9)

220 (38.7)

238 (44.3)

0.017

<0.001

0.100

  1. CAD coronary artery disease, IS ischemic stroke, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol. The value of triglyceride was presented as median (interquartile range), the difference between CAD/IS patients and controls was determined by the Wilcoxon-Mann-Whitney test. P1, CAD vs. controls; P2, IS vs. controls; P3, CAD vs. IS