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Table 4 The association between the haplotypes and CAD/IS

From: ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin cholesterol-lowering responses

Haplotypes

Frequency (%)

CAD

IS

Cases (n =582)

CAD (n =534)

IS (n =553)

OR (95% CI)

P

OR (95% CI)

P

C-A-C

6.5

5.5

4.6

0.83 (0.59-1.18)

0.309

0.69 (0.47-1.00)

0.050

C-C-C

64.1

63.9

64.1

0.99 (0.83-1.17)

0.877

0.99 (0.83-1.18)

0.934

G-C-C

27.0

27.3

28.1

1.01 (0.84-1.22)

0.883

1.06 (0.88-1.28)

0.563

  1. Loci are arranged in the order rs4076317, rs7255436 and rs1044250. Haplotype with frequency less than 3% was pooled and not analyzed