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Table 4 The association between the haplotypes and CAD/IS

From: ANGPTL4 variants and their haplotypes are associated with serum lipid levels, the risk of coronary artery disease and ischemic stroke and atorvastatin cholesterol-lowering responses

Haplotypes Frequency (%) CAD IS
Cases (n =582) CAD (n =534) IS (n =553) OR (95% CI) P OR (95% CI) P
C-A-C 6.5 5.5 4.6 0.83 (0.59-1.18) 0.309 0.69 (0.47-1.00) 0.050
C-C-C 64.1 63.9 64.1 0.99 (0.83-1.17) 0.877 0.99 (0.83-1.18) 0.934
G-C-C 27.0 27.3 28.1 1.01 (0.84-1.22) 0.883 1.06 (0.88-1.28) 0.563
  1. Loci are arranged in the order rs4076317, rs7255436 and rs1044250. Haplotype with frequency less than 3% was pooled and not analyzed