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Table 1 Sensitivity and specificity of different screening tools to identify women with excessive VAT accumulation

From: Circulating glutamate concentration as a biomarker of visceral obesity and associated metabolic alterations

  VAT area ≥ 100 cm2 VAT area ≥ 130 cm2
Sensitivity Specificity Sensitivity Specificity
Glutamate ≥34.6 μmol/L 83% 71% 79% 59%
MetS 52% 83% 57% 77%
HTW 35% 91% 36% 86%
  1. The optimal glutamate concentration threshold (≥34.6μmol/L) was determined with Youden’s Index calculations (J= sensitivity + specificity – 1). Sensitivity and specificity were defined as true positive/(true positive + false negative) and true negative/(true negative + false positive) respectively. MetS: metabolic syndrome, i.e. three or more of the following features: WC >88cm, TG ≥1.7mmol/L, HDL <1.3mmol/L, fasting glucose ≥5.6mmol/L and diastolic blood pressure (BP) ≥130mmHg or systolic BP ≥85mmHg; HTW: hypertriglyceridemic waist, i.e. WC ≥85cm and TG ≥1.5mmol/L