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Table 1 Clinical characteristics of the participants stratified by coffee consumption

From: Coffee consumption is positively related to insulin secretion in the Shanghai High-Risk Diabetic Screen (SHiDS) Study

 

Non-coffee (n = 818)

Coffee (n = 510)

Total (n = 1328)

P

Male (n, %)

330 (40.34%)

210 (41.18%)

540 (40.66%)

0.763

Age, years (mean, SD)

52.80 (14.22)

48.34 (14.49)

51.08 (14.47)

<  0.001

Weight, kg (mean, SD)

65.07 (12.60)

69.99 (14.24)

66.95 (13.46)

<  0.001

BMI, kg/m2 (mean, SD)

23.96 (3.65)

25.18 (4.08)

24.43 (3.87)

<  0.001

Waist, cm (mean, SD)

86.46 (10.19)

88.79 (11.07)

87.35 (10.59)

<  0.001

Fat, % (mean, SD)

28.37 (7.70)

29.81 (8.25)

28.91 (7.94)

0.004

SBP, mmHg (mean, SD)

130.39 (18.17)

130.23 (17.41)

130.33 (17.88)

0.880

DBP, mmHg (mean, SD)

79.02 (10.93)

79.20 (11.33)

79.09 (11.09)

0.776

Diabetic family history (n, %)

351 (44.94%)

249 (50.82%)

1271 (47.21%)

0.041

Hypertension (n, %)

279 (34.15%)

160 (31.37%)

1327 (33.08%)

0.296

Dislipidemia (n, %)

249 (30.48%)

168 (33.01%)

1326 (31.45%)

0.335

Higher Education (n, %)

370 (45.23%)

312 (61.18%)

1328 (51.36%)

<  0.001

Current smoke (n, %)

104 (12.73%)

91 (17.88%)

1326 (14.71%)

0.010

Current alcohol intake (n, %)

115/703 (14.06%)

107/402 (21.02%)

222 (16.73%)

0.001

Tea consumption (n, %)

293 (35.91%)

321 (62.94%)

1326 (46.30%)

<  0.001

Frequent physical activity (n, %)

629 (76.99%)

385 (75.49%)

1327 (76.41%)

0.532

FPG, mmol/L (median, IQR)

6.15 (5.46–7.06)

6.04 (5.36–7.14)

6.11 (5.42–7.08)

0.259

PG30min, mmol/L (median, IQR)

10.67 (9.09–12.38)

10.47 (9.05–12.27)

10.60 (9.07–12.35)

0.188

PG1h, mmol/L (median, IQR)

12.29 (9.79–15.25)

12.19 (9.43–14.97)

12.25 (9.68–15.14)

0.148

PG2h, mmol/L (median, IQR)

10.02 (7.36–14.31)

9.53 (7.09–13.47)

9.85 (7.28–14.06)

0.024

PG3h, mmol/L (median, IQR)

6.69 (4.84–9.62)

6.30 (4.55–8.97)

6.45 (4.74–9.35)

0.016

FIN, uIU/mL (median, IQR)

8.43 (5.75–12.61)

10.10 (6.94–16.22)

9.08 (6.02–13.81)

<  0.001

IN30min, uIU/mL (median, IQR)

44.05 (27.52–69.97)

58.09 (34.50–93.70)

48.21 (28.82–80.23)

<  0.001

IN1h, uIU/mL (median, IQR)

64.58 (40.18–101.45)

77.03 (50.30–121.83)

69.20 (44.25–107.50)

<  0.001

IN2h, uIU/mL (median, IQR)

69.91 (45.83–115.70)

81.54 (51.53–128.38)

74.75 (48.05–119.05)

0.002

IN3h, uIU/mL (median, IQR)

32.22 (17.34–57.65)

34.29 (18.23–62.04)

32.75 (17.64–58.38)

0.237

HbA1c, % (median, IQR)

6.00 (5.60–6.50)

5.90 (5.50–6.60)

5.90 (5.60–6.50)

0.855

GA, % (median, IQR)

14.30 (12.80–16.60)

13.85 (12.40–16.70)

14.10 (12.70–16.68)

0.263

Newly diagnosed diabetes (n, %)

381 (46.58%)

213 (41.76%)

594 (44.73%)

0.037

Impaired glucose regulation (n, %)

237 (28.97%)

148 (29.02%)

385 (28.99%)

0.241

HOMA-β (mean, SD)

84.30 (89.77)

104.65 (103.29)

92.11 (95.66)

<  0.001

HOMA-IR (median, IQR)

2.37 (1.49–3.71)

2.80 (1.75–4.61)

2.52 (1.60–4.04)

<  0.001

Stumvoll first phase (mean, SD)

459.97 (1096.52)

717.67 (1060.32)

558.85 (1089.60)

<  0.001

Stumvoll second phase (mean, SD)

179.32 (248.52)

242.04 (246.55)

203.33 (249.54)

<  0.001

  1. Continuous variables were compared by t-test while classified variable by chi-square test
  2. Variables with approximately normal distribution were presented as means ± standard deviation while those with skew distribution were shown as median (inter quartile range) and classified variable as frequencies and percentages
  3. Abbreviations: SD standard deviation, IQR inter quartile range, BMI body mass index, SBP systolic pressure, DBP diastolic pressure, FPG fasting plasma glucose, PG30min 30-min postprandial plasma glucose, PG1h 1-h postprandial plasma glucose, PG2h 2-h postprandial plasma glucose, PG3h 3-h postprandial plasma glucose, HbA1c glycosylated hemoglobin A1c, GA glycated albumin, FIN fasting serum insulin, IN30min 30-min postprandial serum insulin, IN1h 1-h postprandial serum insulin, IN2h 2-h postprandial serum insulin, IN3h 3-h postprandial serum insulin, HOMA-IR homeostatic model assessment of insulin resistance, HOMA-β, homeostatic model assessment of β-cell function