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Fig. 1 | Nutrition & Metabolism

Fig. 1

From: Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice

Fig. 1

The effect of GP on body weight, food intake, lipid profiles in liver, serum ALT and serum AST. a Strategical abstract of the experimental processes. b Body weight per mouse during the experiment. c Food intake during the treatment of GP. d Triglycerides content, total cholesterol content and free cholesterol in liver which were both corrected by the corresponding protein value (n = 10–11 per group). e Gross morphology of liver tissue selected randomly from four groups and histological analysis of the liver tissue (HE staining × 100 and Oil red O staining × 200). Representative images were shown. Black arrows indicated hepatocellular ballooning and red arrows indicated lobular inflammatory foci. f NAFLD activity score, a histological scoring system for NAFLD, was examined, including steatosis grade, lobular inflammation and hepatocellular ballooning (n = 6–9 per group). g Serum ALT and AST were examined at the end of the experiment (n = 8–9 per group). Error bars represent the standards deviation. Statistical analyses were done with one-way ANOVA,*P<0.05,**P<0.01 versus CD;#P<0.05,##P<0.01 versus HFD

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