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Fig. 9 | Nutrition & Metabolism

Fig. 9

From: Effect of the lipoxygenase inhibitor baicalein on bone tissue and bone healing in ovariectomized rats

Fig. 9

Gene expression analysis at the osteotomy site of the tibia. The expression of arachidonate 5-lipoxygenase (5-lox, a), 12-lipoxygenase (12-lox, b) and 15-lipoxygenase (15-lox, c) were determined to analyse the baicalein effect at the mRNA level. Furthermore, the expression of genes involved in bone metabolism, such as alkaline phosphatase (Ap, d), osteocalcin (OC, e), tartrate-resistant acid phosphatase (Trap, f), receptor activator of nuclear factor kappa B ligand (Rankl, g), transforming growth factor alpha (Tgf-α, h), interleukin-6 (Il-6, i), interleukin-7 (Il-7, j) and insulin-like growth factor (Igf-1, k), were analysed. ***p ≤ 0.001, **p ≤ 0.01, *p ≤ 0.05 (NON-OVX n = 8, OVX n = 9, C1 n = 9, C2 n = 8, C3 n = 8)

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