|
Variables
|
Nanocurcumin (n = 42) Mean(SD)
|
Placebo (n = 42) Mean(SD)
|
P-value
|
|---|
|
Weight (kg)
|
86.54(10.98)
|
86.70(11.15)
|
0.9*
|
|
BMI (kg/m2)
|
30.67(2.14)
|
30.75(2.35)
|
0.9**
|
|
Waist circumference (cm)
|
105.4(6.2)
|
103.8(6.7)
|
0.8*
|
|
Fat Mass (%)
|
31.6(6.4)
|
31.9(4.7)
|
0.8*
|
|
SBP (mmhg)
|
120.3(4.7)
|
120.7(4.3)
|
0.7**
|
|
DBP (mmhg)
|
78.8(4.5)
|
79.8(4.3)
|
0.1*
|
|
ALT (u/l)
|
42.8(11.6)
|
42.1(8.2)
|
0.7**
|
|
AST (u/l)
|
28.4(6.7)
|
27.6(7.8)
|
0.4**
|
|
TC (mg/dl)
|
212.9(18.9)
|
211.8(21.4)
|
0.8*
|
|
LDL-c (mg/dl)
|
135.6(17.6)
|
133.0(20.7)
|
0.6*
|
|
TG (mg/dl)
|
175.9(70.3)
|
181.2(65.6)
|
0.7**
|
|
HDL-c (mg/dl)
|
41.8(5.6)
|
42.7(5.7)
|
0.4*
|
|
FBS (mg/dl)
|
89.1(5.4)
|
89.3(5.8)
|
0.9*
|
|
HbA1c (%)
|
5.2(0.2)
|
5.3(0.2)
|
0.4**
|
|
Nesfatin (ng/ml)
|
1.8(0.5)
|
1.8(0.4)
|
0.5*
|
|
FBI (μIU/ml)
|
8.0(0.5)
|
7.9(0.6)
|
0.7*
|
|
TNF-α (ng/l)
|
14.7(3.3)
|
15.1(2.7)
|
0.2*
|
|
IL-6 (ng/l)
|
7.6(1.5)
|
7.9(1.5)
|
0.2*
|
|
hs-CRP (mg/l)
|
5.9(2.5)
|
5.3(2.5)
|
0.2**
|
|
HOMA-IR (score)
|
1.77(0.16)
|
1.75(0.17)
|
0.7**
|
|
QUICKI (score)
|
0.3505(0.0049)
|
0.3509(0.0057)
|
0.7*
|
- *t-test; **Mann-Whitney; ALT alanine transaminase, AST aspartate transaminase, BMI body mass index, FBI fasting blood insulin,FBS fasting blood sugar, HOMA-IR homeostasis model assessment-insulin resistance, hs-CRP high-sensitive C-reactive protein, HDL-C high density lipoprotein-cholesterol, IL-6 interleukin-6, LDL-C low density lipoprotein-cholesterol, QUICKI quantitative insulin sensitivity check index, TC total cholesterol, TNF-α tumor necrosis factor-alpha
