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Table 4 Effect of SCLE on liver lipid metabolism related enzymes activity in liver (IU/mg protein)

From: Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice

 

FAS

CAT

ACO

AMPK

Control

0.20 ± 0.01a

0.87 ± 0.05a

0.62 ± 0.02c

0.28 ± 0.01ab

HFD

0.19 ± 0.01a

0.70 ± 0.04b

1.02 ± 0.03b

0.25 ± 0.01b

HFD + 0.25% SCLE

0.19 ± 0.01a

0.72 ± 0.02ab

0.96 ± 0.07b

0.30 ± 0.01ab

HFD + 0.5% SCLE

0.16 ± 0.01a

0.82 ± 0.06ab

1.07 ± 0.05b

0.32 ± 0.03a

HFD + 1.0% SCLE

0.18 ± 0.01a

0.89 ± 0.05a

1.43 ± 0.02a

0.33 ± 0.02a

  1. Values are means ± SEM of 10 mice. Means within the same column but not sharing the same superscript letter are significantly different (P < 0.05)
  2. ACC: acetyl-CoA carboxylase; FAS: fatty acid synthase; CAT: carnitine acyltransferase; ACO: acyl-CoA oxidase; AMPK: AMP-activated protein kinase