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Table 4 SdLDL-c mediated fraction of the effect of waist circumference on MetS–related parameters

From: Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation

Outcome

Total

Direct

Mediated

Mediated%

BMI, kg/m2

0.2495

(0.2375,0.2615)

0.2488

(0.2367,0.2610)

0.0007

(−0.0009,0.0025)

–

P value

< 0.001

< 0.001

> 0.05

–

TG, mmol/L

0.0277

(0.0170,0.0385)

0.0171

(0.0073,0.0268)

0.0107

(0.0059,0.0156)

38.63

(21.30,56.32)

P value

< 0.001

< 0.001

< 0.05

< 0.05

HDL, mmol/L

−0.0054

(−0.0075,-0.0032)

− 0.0062

(− 0.0084,-0.0040)

0.0008

(0.0004,0.0014)

–

P value

< 0.001

< 0.001

< 0.05

–

SBP, mmHg

0.3605

(0.2452,0.4759)

0.3625

(0.2461,0.4789)

−0.0020

(− 0.0178,0.0140)

–

P value

< 0.001

< 0.001

> 0.05

–

DBP, mmHg

0.2186

(0.1325,0.3047)

0.2174

(0.1305,0.3044)

0.0012

(−0.0105,0.0141)

–

P value

< 0.001

< 0.001

> 0.05

–

FPG, mmol/L

0.0074

(0.0029,0.0118)

0.0063

(0.0019,0.0108)

0.0010

(0.0004,0.0019)

13.51

(5.41,25.68)

P value

0.001

0.005

< 0.05

< 0.05

hsCRP, mg/L

0.0382

(0.0121,0.0642)

0.0359

(0.0096,0.0621)

0.0023

(−0.0016,0.0068)

–

P value

0.004

0.008

> 0.05

–

  1. The total effect, direct effect, and sdLDL-c mediated effect of waist circumference on each MetS-related parameter and the proportion of the total effect of waist circumference that is mediated by sdLDL-c were showed in the table; The 95% CI was calculated by nonparametric bootstrapping, Process Macro for SPSS; The model was adjusted for age, smoking, drinking and physical activity