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Table 4 SdLDL-c mediated fraction of the effect of waist circumference on MetS–related parameters

From: Small dense LDL cholesterol is associated with metabolic syndrome traits independently of obesity and inflammation

Outcome Total Direct Mediated Mediated%
BMI, kg/m2 0.2495
(0.2375,0.2615)
0.2488
(0.2367,0.2610)
0.0007
(−0.0009,0.0025)
P value < 0.001 < 0.001 > 0.05
TG, mmol/L 0.0277
(0.0170,0.0385)
0.0171
(0.0073,0.0268)
0.0107
(0.0059,0.0156)
38.63
(21.30,56.32)
P value < 0.001 < 0.001 < 0.05 < 0.05
HDL, mmol/L −0.0054
(−0.0075,-0.0032)
− 0.0062
(− 0.0084,-0.0040)
0.0008
(0.0004,0.0014)
P value < 0.001 < 0.001 < 0.05
SBP, mmHg 0.3605
(0.2452,0.4759)
0.3625
(0.2461,0.4789)
−0.0020
(− 0.0178,0.0140)
P value < 0.001 < 0.001 > 0.05
DBP, mmHg 0.2186
(0.1325,0.3047)
0.2174
(0.1305,0.3044)
0.0012
(−0.0105,0.0141)
P value < 0.001 < 0.001 > 0.05
FPG, mmol/L 0.0074
(0.0029,0.0118)
0.0063
(0.0019,0.0108)
0.0010
(0.0004,0.0019)
13.51
(5.41,25.68)
P value 0.001 0.005 < 0.05 < 0.05
hsCRP, mg/L 0.0382
(0.0121,0.0642)
0.0359
(0.0096,0.0621)
0.0023
(−0.0016,0.0068)
P value 0.004 0.008 > 0.05
  1. The total effect, direct effect, and sdLDL-c mediated effect of waist circumference on each MetS-related parameter and the proportion of the total effect of waist circumference that is mediated by sdLDL-c were showed in the table; The 95% CI was calculated by nonparametric bootstrapping, Process Macro for SPSS; The model was adjusted for age, smoking, drinking and physical activity
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