Fig. 6From: Resveratrol attenuates oxidative injury in human umbilical vein endothelial cells through regulating mitochondrial fusion via TyrRS-PARP1 pathwayProposed mechanism for RSV in the regulation of PA-induced oxidative stress in HUVECs. Under the stimulation of PA, HUVECs suffer from oxidative stress. In the treatment of RSV, TyrRS-PARP1 pathway is activated, which then promotes the expression of mitochondrial fusion proteins (OPA1, MFN1/2). The enhancing of mitochondrial fusion finally reduces the oxidative stress in HUVECsBack to article page