Skip to main content

Table 3 Differentially expressed proteins involved in the TCA cycle, fatty acid beta-oxidation, and electron transport chain

From: Maternal diet deficient in riboflavin induces embryonic death associated with alterations in the hepatic proteome of duck embryos

UniProtKB ID

Protein description

Protein name

% coverage

Peptides number

Unique peptides

Fold change*

P-Value

Co-factor

TCA cycle

 U3IHF6

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

SDHA

32.23

17

17

−5.17

2.24E-08

FAD

 U3J5X3

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

SDHB

41.01

11

11

−4.80

5.56E-05

 

 U3IR48

Dihydrolipoyl dehydrogenase

DLD

42.38

18

18

−4.54

1.91E-05

FAD

 U3J6J0

Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

SUCLG1

36.34

7

7

−2.74

9.55E-03

 

 U3INY2

Dihydrolipoamide S-succinyltransferase

DLST

31.87

12

12

−1.94

2.55E-02

 

 R0L7Q0

Fumarate hydratase

FH

59.83

26

26

−1.62

3.80E-03

 

 U3I2P1

Isocitrate dehydrogenase [NAD] subunit, mitochondrial

IDH3A

28.88

8

8

3.48

6.67E-03

 

Fatty acid beta-oxidation

 R0L018

Carnitine O-palmitoyltransferase I, liver isoform

CPT1A

46.10

35

35

−5.45

2.10E-14

 

 U3INM7

Carnitine palmitoyltransferase 2

CPT2

49.62

33

33

−5.20

5.00E-09

 

 U3IR48

Dihydrolipoyl dehydrogenase

DLD

42.38

18

18

−4.54

1.91E-05

FAD

 R0LSV8

Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

ETFDH

47.37

25

25

−4.33

4.08E-09

FAD

 U3 IU30

Acyl-CoA synthetase long chain family member 1

ACSL1

58.08

43

40

−4.23

1.38E-09

 

 U3IAY7

Acyl-CoA dehydrogenase long chain

ACADL

50.70

26

26

−3.57

4.72E-08

FAD

 U3J4Z9

Acyl-CoA synthetase long chain family member 5

ACSL5

40.85

24

21

−3.05

7.07E-07

 

 U3IFL0

Solute carrier family 25 member 20

SLC25A20

38.01

9

9

−2.90

4.26E-04

 

 U3J7F4

Electron transfer flavoprotein alpha subunit

ETFA

62.87

17

17

−2.69

1.46E-02

FAD

 U3J8W0

Acyl-CoA dehydrogenase short chain

ACADS

49.30

14

14

−2.36

4.32E-03

FAD

 U3IFB0

2,4-dienoyl-CoA reductase 1

DECR1

39.20

9

9

−2.32

2.32E-02

 

 U3I806

Trifunctional enzyme subunit alpha, mitochondrial

HADHA

53.42

39

38

−2.03

6.79E-03

 

 U3IK00

Carnitine palmitoyltransferase 1B

CPT1B

17.83

7

7

−1.89

2.53E-03

 

 U3J1J0

Acyl-CoA dehydrogenase family member 9

ACAD9

60.22

33

33

−1.73

4.14E-04

FAD

 U3ILK4

Enoyl-CoA delta isomerase 1, mitochondrial

ECI1

50.00

11

11

−1.67

1.13E-02

 

 U3IHS8

Carnitine O-acetyltransferase

CRAT

34.71

22

22

−1.67

8.38E-04

 

ETC

 U3IHF6

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

SDHA

32.23

17

17

−5.17

2.24E-08

FAD

 U3J5X3

Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

SDHB

41.01

11

11

−4.80

5.56E-05

 

 R0K082

NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

NDUFS1

55.59

34

34

−2.79

1.02E-06

 

 R0LIL9

ATP synthase subunit O, mitochondrial

ATP5PO

69.02

13

13

−2.56

4.03E-03

 

 U3IKH0

NADH:ubiquinone oxidoreductase core subunit V2

NDUFV2

64.22

12

12

−2.56

3.46E-02

 

 U3 J175

ATP synthase peripheral stalk-membrane subunit b

ATP5PB

45.61

15

15

−2.41

4.63E-03

 

 U3IK89

ATP synthase F1 subunit gamma

ATP5F1C

28.27

15

15

−2.40

4.90E-04

 

 U3I5C5

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

NDUFA9

48.81

16

16

−2.19

2.25E-02

FAD

 U3J3L1

NADH:ubiquinone oxidoreductase core subunit V1

NDUFV1

47.16

11

11

−1.99

9.78E-03

FMN

 U3I8R9

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

NDUFA10

36.34

11

11

−1.96

5.89E-03

FAD

 U3 J741

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

NDUFA12

65.63

7

7

−1.77

4.88E-02

 

 U3J1J0

Acyl-CoA dehydrogenase family member 9

ACAD9

60.22

33

33

−1.73

4.14E-04

FAD

 U3I342

Ubiquinol-cytochrome c reductase core protein 2

UQCRC2

61.49

26

26

−1.71

4.82E-03

 

 U3IMS0

NADH:ubiquinone oxidoreductase core subunit S3

NDUFS3

55.45

13

13

−1.56

9.70E-03

 
  1. TCA tricarboxylic acid, ETC electron transport chain, FMN flavin mononucleotide, FAD flavin adenine dinucleotide
  2. *Fold change is expressed as the ratio of the riboflavin-deficient to the control group. For diminished proteins, the fold change was transformed to the corresponding negative value
Back to article page

Nutrition & Metabolism

ISSN: 1743-7075

Contact us