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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Myricetin improves endurance capacity by inducing muscle fiber type conversion via miR-499

Fig. 5

The effects of myricetin on regulating miR-499/Sox6 axis in vivo and in vitro. The mRNA expressions of Myh7b (a: soleus; b: gastrocnemius), miR-499 (c: soleus; d: gastrocnemius) and Sox6 (e: soleus; f: gastrocnemius) in rats were determined by Real-time PCR. Protein levels of Sox6 (g) in soleus and gastrocnemius muscles were measured by immunoblotting. The mRNA expressions of miR-499 (h), Myh7b (i), Sox6 (j), and PGC-1α (l) in L6 myotubes were determined by Real-time PCR. Protein levels of Sox6 (k) and PGC-1α (m) in L6 myotubes were measured by immunoblotting. Data are presented as mean ± SD. *P<0.05, **P<0.01, ***P<0.001

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