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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Plasma metabolomic profiling of proliferative diabetic retinopathy

Fig. 5

Non-targeted metabolomics pathway analysis. a Pathway enrichment analysis. The size and color of each circle was based on pathway impact value and p-value, respectively. b 9 pathways differ between the NDR and PDR group, particularly, in Pyrimidine metabolism, Alanine, aspartate and glutamate metabolism, Caffeine metabolism, beta-Alanine metabolism, Purine metabolism, Cysteine and methionine metabolism, Sulfur metabolism, Sphingolipid metabolism, Arginine and proline metabolism. c Heatmap of non-targeted plasma metabolomics show 63 compounds play important roles in 9 above-mentioned pathways indicated significantly different metabolites between NDR and PDR group

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