Table 2 Metabolite markers identified from discovery metabolomic profiling
From: Plasma metabolomic profiling of proliferative diabetic retinopathy
Metabolite | Fold-Change (PDR/NDR) | Vip | Elements | Query_mass | Adduct | Trend | AUC | P-value |
|---|---|---|---|---|---|---|---|---|
Fumaric acid | 4.235 | 1.1898 | HMDB0000134 | 114.9904 | M-H | ↑ | 0.96 | 7.90E-17 |
Uridine | 4.2748 | 1.1764 | HMDB0000296 | 243.0613 | M-H | ↑ | 0.95 | 6.10E-16 |
Acetic acid | 2.1932 | 1.9268 | HMDB0000042 | 60.9867 | M + H | ↑ | 1.0 | 1.48E-13 |
Cytidine | 8.6763 | 1.0932 | HMDB0000089 | 242.0796 | M-H | ↑ | 0.95 | 5.87E-12 |
3-Sulfinoalanine | 0.57541 | 1.155 | HMDB0000996 | 151.9927 | M-H | ↓ | 1 | 1.06E-11 |
3-Methylxanthine | 4.5202 | 1.0224 | HMDB0001886 | 165.0393 | M-H | ↑ | 0.96 | 1.02E-09 |
Sulfate | 1.8943 | 1.3454 | HMDB0001448 | 96.9718 | M + H | ↑ | 0.96 | 2.28E-05 |