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Table 3 Regression coefficients [β (95% CI)] for fetal development associated with categories of SF, ST and their ratio

From: Iron deficiency in late pregnancy and its associations with birth outcomes in Chinese pregnant women: a retrospective cohort study

 

Gestational age (weeks)a

Birth weight (g)b

Birth length (cm)b

SF (μg/L)

 <  8.3

0

0

0

 8.3–11.5

0.09 (0.01, 0.18)*

−25.56 (−45.36, −5.77)*

−0.33 (− 0.57, − 0.09)**

 11.6–20.2

− 0.08 (− 0.17, 0.02)

−59.63 (−80.30, −38.97)**

−0.31 (− 0.57, − 0.05)*

 >  20.2

−0.09 (− 0.19, 0.01)

−85.41 (− 108.23, − 62.60)**

−0.53 (− 0.81, − 0.25)**

 P for trend

0.0039

< 0.0001

0.0023

ST (g/L)

 < 3.64

0

0

0

 3.64–4.08

0.15 (0.06, 0.24)**

33.51 (14.29, 52.73)**

−0.18 (− 0.42, 0.05)

 4.09–4.58

0.25 (0.16, 0.33)**

56.15 (36.19, 76.11)**

−0.37 (− 0.62, − 0.13)**

 >  4.58

0.27 (0.19, 0.36)**

76.29 (56.00, 96.58)**

−0.60 (− 0.85, − 0.35)**

 P for trend

< 0.0001

< 0.0001

< 0.0001

ST/SF ratio log10 transform

 <  5.28

0

0

0

 5.28–5.54

0.05 (− 0.04, 0.14)

27.31 (7.46, 47.16)**

0.13 (− 0.12, 0.37)

 5.55–5.72

0.23 (0.15, 0.32)**

57.83 (36.69, 78.98)**

0.08 (−0.17, 0.33)

 >  5.72

0.18 (0.08, 0.28)**

97.04 (74.28,119.81)**

0.22 (−0.06, 0.49)

 P for trend

< 0.0001

< 0.0001

0.1773

  1. a Adjusted for maternal age, gravidity, parity, gestational age, BMI, systolic and diastolic BP at delivery, GDM, ICP, PE, PIH, infants sex, hsCRP (mg/L)and hemoglobin(g/L)
  2. b Additionally adjusted for gestational age
  3. *p < 0.05, **p < 0.01
  4. Abbreviations: CI confidence interval,SF serum ferritin, ST serum transferrin, BMI body mass index, BP blood pressure, GDM gestational diabetes mellitus, ICP intrahepatic cholestasis of pregnancy, PE Preeclampsia, PIH pregnancy-induced hypertension, hsCRP high sensitivity C-reactive protein