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Table 5 ORs and 95% CIs for different pregnancy outcomes with categories of SF, ST and their ratio

From: Iron deficiency in late pregnancy and its associations with birth outcomes in Chinese pregnant women: a retrospective cohort study

  GDM ICP PE PIH PTB LBW Macrosomia SGA LGA
Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI)
SF (μg/L)
 <  8.3 1 1 1 1 1 1 1 1 1
 8.3–11.5 1.01 (0.81, 1.26) 1.52 (1.18, 1.95)** 1.40 (0.98, 1.99) 1.32 (0.87, 2.00) 0.81 (0.64, 1.02) 1.55 (1.02, 2.36)* 1.02 (0.84, 1.26) 1.33 (1.06, 1.65)* 0.97 (0.84, 1.13)
 11.6–20.2 1.19 (0.95, 1.49) 2.39 (1.85, 3.08)** 1.99 (1.41, 2.82)** 1.47 (0.95, 2.27) 1.23 (0.98, 1.56) 1.91 (1.25, 2.92)** 0.85 (0.68, 1.07) 1.48 (1.18, 1.85)** 0.84 (0.72, 0.99)*
 >  20.2 1.56 (1.24, 1.95)** 3.42 (2.64, 4.43)** 3.34 (2.33, 4.81)** 1.58 (1.01, 2.48)* 1.20 (0.93, 1.55) 2.15 (1.39, 3.33)** 0.72 (0.56, 0.94)* 1.82 (1.44, 2.29)** 0.77 (0.64, 0.93)**
P for trend < 0.0001 < 0.0001 < 0.0001 0.112 0.036 < 0.0001 0.005 < 0.0001 0.0037
ST (g/L)
 < 3.64 1 1 1 1 1 1 1 1 1
 3.64–4.08 0.99 (0.81, 1.21) 1.07 (0.85, 1.36) 0.88 (0.66, 1.17) 0.94 (0.65, 1.37) 0.78 (0.64, 0.96)* 0.81 (0.56, 1.16) 1.29 (1.01, 1.63)* 0.81 (0.68, 0.98)* 1.14 (0.96, 1.34)
 4.09–4.58 1.17 (0.96, 1.43) 1.24 (0.98, 1.56) 0.74 (0.54, 1.00)* 1.02 (0.70, 1.49) 0.56 (0.45, 0.70)** 0.78 (0.53, 1.17) 1.78 (1.42, 2.24)** 0.82 (0.68, 0.99)* 1.46 (1.24, 1.71)**
 >  4.58 1.48 (1.21, 1.80)** 1.59 (1.26, 1.99)** 0.78 (0.57, 1.06) 1.32 (0.91, 1.91) 0.53 (0.43, 0.67)** 0.59 (0.39, 0.88)** 1.65 (1.31, 2.09)** 0.72 (0.59, 0.88)** 1.48 (1.26, 1.74)**
P for trend < 0.0001 < 0.0001 0.0795 0.1312 < 0.0001 0.0118 < 0.0001 0.0018 < 0.0001
ST/SF ratio log10 transform
 <  5.28 1 1 1 1 1 1 1 1 1
 5.28–5.54 0.75 (0.62, 0.90)** 0.82 (0.67, 1.00) 0.67 (0.51, 0.88)** 1.03 (0.72, 1.45) 0.94 (0.76, 1.16) 0.84 (0.58, 1.21) 1.16 (0.92, 1.47) 0.83 (0.69, 0.99)* 1.05 (0.89, 1.24)
 5.55–5.72 0.68 (0.55, 0.83)** 0.50 (0.40, 0.63)** 0.51 (0.37, 0.69)** 0.78 (0.53, 1.14) 0.57 (0.45, 0.73)** 0.69 (0.46, 1.03) 1.49 (1.17, 1.88)** 0.69 (0.56, 0.84)** 1.28 (1.08, 1.52)**
 >  5.72 0.75 (0.60, 0.94)* 0.41 (0.32, 0.53)** 0.33 (0.22, 0.48)** 0.85 (0.55, 1.32) 0.67 (0.52, 0.86)** 0.36 (0.23, 0.57)** 1.44 (1.12, 1.86)** 0.51 (0.41, 0.65)** 1.39 (1.16, 1.66)**
P for trend < 0.0001 < 0.0001 < 0.0001 0.2983 < 0.0001 0.0001 0.0011 < 0.0001 < 0.0001
  1. Odds ratios were adjusted for maternal age, BMI, gravidity, parity, hsCRP (mg/L) and hemoglobin (g/L). Parameters of PTB were additionally corrected for GDM, ICP, PE, PIH, systolic and diastolic BP, and infant sex. The values of SGA, LGA, LBW and macrosomia were additionally corrected for gestational age at delivery.*p < 0.05, **p < 0.01
  2. Abbreviations: ID iron deficiency, SF serum ferritin, ST serum transferrin, OR Odds ratio. CI confidence interval, GDM gestational diabetes mellitus, ICP intrahepatic cholestasis of pregnancy, PE Preeclampsia, PIH pregnancy-induced hypertension, PTB pre-term birth, LBW Low birth weight, SGA/LGA small/large for gestational age, BMI body mass index, hsCRP high sensitivity C-reactive protein, BP blood pressure