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Table 3 Comparison of demographic, lifestyle characteristics and serum lipid levels between the normal and CAD groups. HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Apo, Apolipoprotein. 1Mean ± SD determined by t-test.2Because of not normally distributed, the value of triglyceride was presented as median (interquartile range), the difference between the two groups was determined by the Wilcoxon-Mann-Whitney test

From: A novel lncRNA-miRNA-mRNA triple network identifies lncRNA TWF1 as an important regulator of miRNA and gene expression in coronary artery disease

Parameter

Control

CAD

test-statistic

P

Number

424

433

  

Male/female

128/296

141/292

0.672

0.412

Age (years)1

55.31 ± 10.52

55.87 ± 11.13

0.987

0.378

Height (cm)

156.23 ± 6.91

155.53 ± 7.03

1.596

0.212

Weight (kg)

52.86 ± 7.84

60.74 ± 10.84

21.439

1.72E-005

Body mass index (kg/m2)

29.59 ± 3.23

32.31 ± 6.54

32.224

2.48E-008

Waist circumference (cm)

73.43 ± 6.61

87.45 ± 9.87

23.122

3.34E-005

Smoking status [n (%)]

 Non-smoker

313(74.0)

288(65.2)

  

 Smoker

110(26.0)

154(34.8)

7.690

0.005

Alcohol consumption [n (%)]

 Non-drinker

322(76.1)

330(74.5)

  

 Drinker

101(23.9)

113(25.5)

0.309

0.578

Systolic blood pressure (mmHg)

128.24 ± 18.18

129.47 ± 22.16

0.403

0.421

Diastolic blood pressure (mmHg)

81.54 ± 10.16

82.49 ± 13.15

0.807

0.393

Pulse pressure (mmHg)

49.64 ± 14.13

50.42 ± 14.59

1.492

0.233

Glucose (mmol/L)

5.92 ± 1.86

7.45 ± 2.25

18.817

5.93E-005

Total cholesterol (mmol/L)

4.91 ± 1.13

5.24 ± 1.07

8.121

0.019

Triglyceride (mmol/L)2

1.49(0.51)

1.53(1.22)

2.137

0.187

HDL-C (mmol/L)

1.52 ± 0.44

1.06 ± 0.26

8.673

0.013

LDL-C (mmol/L)

2.84 ± 0.84

2.88 ± 0.79

9.497

0.007

ApoA1 (g/L)

1.23 ± 0.25

1.17 ± 0.27

0.384

0.518

ApoB (g/L)

0.83 ± 0.19

0.89 ± 0.32

1.542

0.193

ApoA1/ApoB

1.67 ± 0.50

1.66 ± 0.57

0.095

0.758

Diabetes [n (%)]

47(11.3)

64(16.7)

5.192

0.023

Hypertension [n (%)]

197(45.4)

213(48.4)

0.795

0.373