Lipid findings from the Diabetes Education to Lower Insulin, Sugars, and Hunger (DELISH) Study

Nutrition & Metabolism

Table 2 Change in standard lipid and NMR LipoProfile (LabCorp) from baseline to 6 months

Source of lipid measure	Lipid measure units	Mean (SD) baseline	Mean (SD) 6 months	Mean (SD) Δ from baseline	N with Δ data	95% CI [LB, UB]	P
Standard	LDL-C mg/dL	92.86 (38.56)	99.89 (36.51)	7.03 (29.93)	53^a	[−1.22, 15.28]	.093
Standard	HDL-C mg/dL	52.79 (16.95)	56.49 (16.97)	3.70 (8.54)	53^a	[1.34, 6.05]	.0027
Standard	Cholesterol, Total mg/dL	176.96 (43.23)	179.83 (44.14)	2.87 (34.30)	53^a	[−6.59, 12.32]	.55
Standard	Triglyceride mg/dL	154.08 (78.25)	117.63 (53.57)	−36.44 (59.64)	52^a,b	[−53.05, −19.84]	.0001
Standard	Triglyceride/HDL-C ratio	3.49 (2.59)	2.38 (1.52)	−1.11 (1.70)	52^a,b	[−1.58, −0.64]	<.0001
Standard	Non-HDL-C cholesterol mg/dL	124.17 (41.92)	123.34 (37.84)	−0.83 (33.22)	53^a	[−9.99, 8.33]	.86
NMR	sLDL-P nmol/L	610.58 (314.92)	493.95 (261.38)	−116.64 (255.70)	55	[−185.76, −47.51]	.0013
NMR	LDL-P nmol/L	1253.04 (430.16)	1246.60 (404.76)	−6.44 (359.33)	55	[−103.58, 90.70]	.89
NMR	LDL Size nm	20.58 (0.61)	20.82 (0.59)	0.24 (0.46)	55	[0.12, 0.37]	.0003
NMR	HDL-P (Total) μm/L	33.62 (7.07)	34.17 (6.54)	0.56 (4.53)	55	[−0.67, 1.78]	.36

Note. LDL-C = calculated low-density lipoprotein cholesterol, HDL-C = calculated high-density lipoprotein cholesterol, Non-HDL-C cholesterol computed as (total cholesterol – HDL-C), sLDL-P = small low-density lipoprotein number, LDL-P = low-density lipoprotein number, LDL size = low-density lipoprotein size; HDL-P (total) = total high-density lipoprotein number
^aAnalysis omits one participant who was missing a baseline standard lipid panel and one participant who did not provide a standard lipid panel at 6 months (n = 2 omitted)
^bAnalysis omits participant who provided a non-fasting sample at baseline (n = 1 omitted). The pattern and statistical significance of results remains if we retain the non-fasted participant
t-test p-value is two-sided. LB = Lower bound, UB=Upper bound

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