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Fig. 8 | Nutrition & Metabolism

Fig. 8

From: Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology

Fig. 8

Spearman correlation analysis between genus species and serological indicators. The abundance of Lactobacillus was negatively correlated with the LPS and IFN-γ. The abundances of Akkermansia and Anaerofustis were negatively correlated with blood glucose of GTT (1 h) and IL-1, and positively correlated with the level of IL-10. In addition, the blood glucose of GTT (1 h) was positively correlated with the abundances of Enterorhabdus, and Mucispirillum. The abundances of Alloprevotella was positively correlated with the level of IL-IL-1, and negatively correlated with IL-10. The results indicated that fucoidan may reduce the level of inflammation and improve the glucose tolerance by regulating gut flora. X-axis, serological indicators; Y-axis, genus species. The depth of color visually shows the correlation between genus species and serological indicators. +, P < 0.05; *, P < 0.01

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