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Table 1 Baseline characteristics according to LAP trajectories

From: Association of lipid accumulation product trajectories with 5-year incidence of type 2 diabetes in Chinese adults: a cohort study

Variablesa Total
(n = 4508)
Low trajectory
(n = 3639)
Moderate trajectory
(n = 800)
High trajectory
(n = 69)
P valueb
Age (years) 42.0 (32.0–57.0) 40.0 (31.0–57.0) 47.0 (38.0–60.8) 40.0 (33.0–48.0) < 0.001
Male (%) 2438 (54.1) 1723 (47.4) 648 (81.0) 67 (97.1) < 0.001
BMI (kg/m2) 23.4 (20.9–25.6) 22.5 (20.5–24.7) 26.3 (24.6–28.0) 27.3 (25.4–29.2) < 0.001
WC (cm) 80.0 (71.0–87.0) 76.0 (70.0–84.0) 89.0 (85.0–94.0) 92.0 (88.0–95.8) < 0.001
Han ethnicity (%) 4339 (96.6) 3500 (96.5) 773 (97.2) 66 (95.7) 0.513
Current smoker (%) 990 (26.6) 614 (20.5) 331 (49.9) 45 (75.0) < 0.001
Current alcohol drinker (%) 2031 (60.2) 1490 (55.0) 487 (80.0) 54 (90.0) < 0.001
Married status (%) 3412 (86.4) 2677 (84.5) 680 (94.2) 55 (93.2) < 0.001
Family history of diabetes (%) 347 (7.7) 279 (7.7) 59 (7.4) 9 (13.0) 0.235
Hypertension (%) 947 (21.7) 634 (18.0) 295 (37.7) 18 (27.3) < 0.001
Use of antihypertensive (%) 407 (9.0) 285 (7.8) 118 (14.8) 4 (5.8) < 0.001
LAP 19.7 (9.9–36.0) 15.4 (8.0–25.7) 56.6 (43.0–75.8) 118.5 (86.6–200.1) < 0.001
Fasting blood concentrations of
 Glucose (mmol/l) 5.0 (4.7–5.3) 4.9 (4.7–5.3) 5.2 (4.8–5.6) 5.2 (4.8–5.8) < 0.001
 Total cholesterol (mmol/l) 4.7 (4.2–5.3) 4.6 (4.1–5.2) 5.1 (4.5–5.8) 5.7 (4.9–6.3) < 0.001
 Triglycerides (mmol/l) 1.14 (0.79–1.67) 1.00 (0.73–1.35) 2.28 (1.71–2.98) 4.5 (3.2–8.1) < 0.001
 HDL (mmol/l) 1.40 (1.15–1.71) 1.48 (1.23–1.78) 1.14 (0.96–1.32) 1.04 (0.85–1.21) < 0.001
 Hemoglobin (g/L) 133.0 (124.0–144.0) 131.0 (123.0–142.0) 144.0 (135.0–150.0) 146.0 (138.0–154.0) < 0.001
 Creatinine (μmol/L) 66.0 (54.0–78.0) 62.0 (53.0–75.0) 75.0 (66.0–84.0) 74.0 (65.0–83.0) < 0.001
 Uric acid (μmol/L) 283.0 (221.0–350.0) 263.0 (210.0–327.0) 359.0 (305.0–418.0) 390.0 (332.0–451.5) < 0.001
  1. BMI body mass index, WC waist circumference, LAP lipid accumulation product, HDL high-density lipoprotein cholesterol
  2. aContinuous variables were summarized as median (interquartile range)
  3. bP values are calculated by Kruskal–Wallis test for continuous variables and chi-square test for categorical variables