Fig. 5
From: Hepatic PKA inhibition accelerates the lipid accumulation in liver
HFD effects on transcriptome of PKAi and control mice. Mice were fed with HFD or CD from 8-week old for 2 months. Liver tissues were harvested to perform the RNA sequencing. a-b The heatmap (a) and top 10 enriched GO terms (b) of DEGs in the liver tissue of control mice fed with CD vs. HFD. c-d The heatmap (c) and top 10 enriched GO terms (d) of DEGs in the liver tissue of PKAi mice fed with CD v.s. HFD. GO terms were ranked by qvalue, the modified Fisher exact P-value. Rich factor indicates the ratio of input gene number to background gene number of each term. (N = 3)